Overview

  • Product name

  • Description

    Rabbit polyclonal to CRIF1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment corresponding to Human CRIF1 aa 84-117.
    Sequence:

    ELEAEEREWYPSLATMQESLRVKQLAEEQKRRER


    Database link: Q8TAE8

  • Positive control

    • A549 cells.
  • General notes

    Previously labelled as GADD45GIP1.

Properties

Applications

Our Abpromise guarantee covers the use of ab220687 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function

    Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • Tissue specificity

    Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • 39S ribosomal protein L59 mitochondrial antibody
    • CKBBP2 antibody
    • CKbetaBP2 antibody
    • CKII beta associating protein antibody
    • CKII beta binding protein 2 antibody
    • CKII beta-associating protein antibody
    • CR6 interacting factor 1 antibody
    • CR6-interacting factor 1 antibody
    • CRIF1 antibody
    • G45IP_HUMAN antibody
    • GADD45G interacting protein 1 antibody
    • Gadd45gip1 antibody
    • Growth arrest and DNA damage inducible GADD45G interacting protein antibody
    • growth arrest and DNA damage inducible, gamma interacting protein 1 antibody
    • Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody
    • MGC4667 antibody
    • MGC4758 antibody
    • MRP L59 antibody
    • p53 responsive gene 6 antibody
    • p53 responsive gene 6 protein antibody
    • p53-responsive gene 6 protein antibody
    • Papillomavirus L2 interacting nuclear protein 1 antibody
    • Papillomavirus L2-interacting nuclear protein 1 antibody
    • PLINP 1 antibody
    • PLINP antibody
    • PLINP-1 antibody
    • PLINP1 antibody
    • PRG6 antibody
    see all

Images

  • Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized A549 cells labeling CRIF1 with ab220687 at 4 µg/mL (green).

References

ab220687 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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