Overview

  • Product name

    Anti-Cripto1/CRIPTO antibody
    See all Cripto1/CRIPTO primary antibodies
  • Description

    Rabbit polyclonal to Cripto1/CRIPTO
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Cripto1/CRIPTO (N terminal).
    Database link: NP_003203

  • Positive control

    • Recombinant Human Cripto1/CRIPTO protein (ab93004) can be used as a positive control in WB. 293 cell lysate.
  • General notes

     This product was previously labelled as Cripto1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab139725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 21 kDa.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function

    Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
  • Tissue specificity

    Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
  • Sequence similarities

    Contains 1 EGF-like domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CR antibody
    • CRGF antibody
    • Cripto 1 antibody
    • Cripto 1 growth factor antibody
    • cripto antibody
    • Cripto-1 growth factor antibody
    • Cripto1 growth factor antibody
    • Epidermal growth factor like cripto protein CR1 antibody
    • Epidermal growth factor-like cripto protein CR1 antibody
    • TDGF 1 antibody
    • TDGF1 antibody
    • TDGF1_HUMAN antibody
    • Teratocarcinoma derived growth factor 1 antibody
    • Teratocarcinoma-derived growth factor 1 antibody
    see all

Images

  • Immunofluorescence of Cripto1/CRIPTO in 293 cells with ab139725 at 20 ug/mL.

  • Anti-Cripto1/CRIPTO antibody (ab139725) at 1 µg/ml + 293 cell lysate at 15 µg

    Predicted band size: 21 kDa

References

This product has been referenced in:

  • Todaro F  et al. Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells 37:332-344 (2019). Read more (PubMed: 30566254) »
  • Tassinari V  et al. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis 6:e1688 (2015). WB . Read more (PubMed: 25766327) »
See all 2 Publications for this product

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