Anti-CRLR antibody - N-terminal (ab140773)
Key features and details
- Rabbit polyclonal to CRLR - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CRLR antibody - N-terminal
See all CRLR primary antibodies -
Description
Rabbit polyclonal to CRLR - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Dog, Pig, Monkey, Gorilla, Common marmoset, Orangutan -
Immunogen
Synthetic peptide corresponding to 15 amino acids from the N-terminal extracellular domain of Human CRLR (NP_005786.1).
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Positive control
- Human colon tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140773 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 16 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 16 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. -
Tissue specificity
Predominantly expressed in the lung and heart. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 100391342 Common marmoset
- Entrez Gene: 488438 Dog
- Entrez Gene: 100054281 Horse
- Entrez Gene: 10203 Human
- Entrez Gene: 54598 Mouse
- Entrez Gene: 100172095 Orangutan
- Entrez Gene: 397172 Pig
- Entrez Gene: 25029 Rat
see all -
Alternative names
- Calcitonin gene related peptide type 1 receptor antibody
- Calcitonin gene-related peptide type 1 receptor antibody
- Calcitonin receptor like antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab140773 has not yet been referenced specifically in any publications.