Overview

  • Product name

    Anti-CRMP2 (phospho T555) antibody [M539]
    See all CRMP2 primary antibodies
  • Description

    Mouse monoclonal [M539] to CRMP2 (phospho T555)
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human CRMP2 (phospho T555). Coupled to carrier protein.
    Database link: Q16555

  • Positive control

    • Rat PC12 cell lysate, stimulated with calyculin A (100 nM).

Properties

Applications

Our Abpromise guarantee covers the use of ab215742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).

Target

  • Function

    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • Post-translational
    modifications

    3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Collapsin response mediator protein 2 antibody
    • Collapsin response mediator protein antibody
    • Collapsin response mediator protein hCRMP 2 antibody
    • CRAM antibody
    • CRMP 2 antibody
    • CRMP-2 antibody
    • CRMP2 antibody
    • DHPRP 2 antibody
    • DHPRP2 antibody
    • Dihydropyrimidinase 2 antibody
    • Dihydropyrimidinase like 2 antibody
    • Dihydropyrimidinase like 2 long form antibody
    • Dihydropyrimidinase related protein 2 antibody
    • Dihydropyrimidinase-related protein 2 antibody
    • DPYL 2 antibody
    • DPYL2 antibody
    • DPYL2_HUMAN antibody
    • DPYSL 2 antibody
    • Dpysl2 antibody
    • DRP-2 antibody
    • DRP2 antibody
    • Musunc 33 antibody
    • Musunc33 antibody
    • N2A3 antibody
    • TOAD 64 antibody
    • TOAD64 antibody
    • ULIP 2 protein antibody
    • ULIP-2 antibody
    • Ulip2 antibody
    • Unc-33-like phosphoprotein 2 antibody
    see all

Images

  • Lanes 1-2 : rabbit anti-CRMP2 (C-terminal region) at 1/500 dilution
    Lanes 3-4 : Anti-CRMP2 (phospho T555) antibody [M539] (ab215742) at 1/500 dilution

    Lanes 1 & 3 : Rat PC12 cell lysate, stimulated with calyculin A (100 nM)
    Lane 2 : Rat PC12 cell lysate, stimulated with calyculin A (100 nM) treated with lambda phosphatase
    Lane 4 : Rat PC12 cell lysate, stimulated with calyculin A (100 nM) treated with lambda phosphatase

    Predicted band size: 62 kDa



    Western blot membranes were incubated with diluted antibody in 5% non-fat milk, PBS, and 0.04% Tween20 for 1 h at room temperature.

References

ab215742 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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