Key features and details
- Rabbit polyclonal to CRMP4
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CRMP4 antibody
See all CRMP4 primary antibodies
DescriptionRabbit polyclonal to CRMP4
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment, corresponding to amino acids 422 - 567 of Human CRMP4 (NM_001387).
- WB: Human fetal brain lysate IHC-P: Human fetal skeletal muscle
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:Add 200 ul sterile distilled water.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab101009 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/2000. Detects a band of approximately 61 kDa (predicted molecular weight: 62 kDa).|
|IHC-P||1/100 - 1/500.|
FunctionNecessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Tissue specificityMainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Sequence similaritiesBelongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
modificationsPhosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Cellular localizationCytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
- Information by UniProt
- Collapsin response mediator protein 4 antibody
- Collapsin response mediator protein 4 long antibody
- CRMP 4 antibody
Anti-CRMP4 antibody (ab101009) at 1/1000 dilution + Human fetal brain lysate
Predicted band size: 62 kDa
Observed band size: 61 kDa why is the actual band size different from the predicted?
ab101009, at a 1/100 dilution, staining CRMP4 in formalin fixed, paraffin embedded Human fetal skeletal muscle. The image shows cytoplasmic staining of the antibody.
ab101009 has been referenced in 1 publication.
- Chen SL et al. Targeting CRMP-4 by lentivirus-mediated RNA interference inhibits SW480 cell proliferation and colorectal cancer growth. Exp Ther Med 12:2003-2008 (2016). WB ; Human . PubMed: 27698685