Overview

  • Product name
  • Description
    Goat polyclonal to CROT / COT
  • Host species
    Goat
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Dog
  • Immunogen

    Synthetic peptide corresponding to Rat CROT/ COT aa 178-199 (internal sequence). NP_114193.1.
    Sequence:

    NYFKTESEGHCPTH


    Database link: P11466

  • Positive control
    • Mouse liver lysates.
  • General notes

    Previously labelled as CROT. 

Properties

Applications

Our Abpromise guarantee covers the use of ab175450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 70 kDa.

Target

  • Function
    Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
  • Pathway
    Lipid metabolism; fatty acid beta-oxidation.
  • Sequence similarities
    Belongs to the carnitine/choline acetyltransferase family.
  • Cellular localization
    Peroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carnitine O octanoyltransferase antibody
    • COT antibody
    • CROT antibody
    • OCTC_HUMAN antibody
    • Peroxisomal carnitine acyltransferase antibody
    • Peroxisomal carnitine O octanoyltransferase antibody
    • Peroxisomal carnitine O-octanoyltransferase antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human liver tissue, staining CROT / COT with ab175450 at 5µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

  • Anti-CROT / COT antibody (ab175450) at 1 µg/ml + mouse liver lysates at 35 µg

    Predicted band size: 70 kDa



    Primary incubation was 1 hour. Detected by chemiluminescence.

References

ab175450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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