Key features and details
- Potent and selective protein kinase D inhibitor. 1 ml water soluble pack.
- Purity: > 99%
- Soluble in 1ml of water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Product nameCRT0066101 (mM/ml), protein kinase D inhibitor
DescriptionPotent and selective protein kinase D inhibitor. 1 ml water soluble pack.
Potent and selective protein kinase D inhibitor (IC50 values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
Chemical name2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 1ml of water to give specified mM/ml concentration
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146740 has not yet been referenced specifically in any publications.