Anti-CRYBB3 antibody - C-terminal (ab174163)

Overview

  • Product name
    Anti-CRYBB3 antibody - C-terminal
  • Description
    Rabbit polyclonal to CRYBB3 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CRYBB3 aa 178-207 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P26998

  • Positive control
    • K562 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab174163 is purified through a protein A column, followed by immunogen affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab174163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 24 kDa.

Target

  • Function
    Crystallins are the dominant structural components of the vertebrate eye lens.
  • Involvement in disease
    Defects in CRYBB3 are the cause of cataract congenital nuclear autosomal recessive type 2 (CATCN2) [MIM:609741]. A congenital cataract affecting the central nucleus of the eye. Nuclear cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders.
  • Sequence similarities
    Belongs to the beta/gamma-crystallin family.
    Contains 4 beta/gamma crystallin 'Greek key' domains.
  • Domain
    Has a two-domain beta-structure, folded into four very similar Greek key motifs.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta B3 crystallin antibody
    • Beta crystallin B3 antibody
    • Beta-B3 crystallin antibody
    • Beta-crystallin B3 antibody
    • CRBB3_HUMAN antibody
    • CRYB3 antibody
    • Crybb3 antibody
    see all

Images

  • Anti-CRYBB3 antibody - C-terminal (ab174163) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size: 24 kDa

References

ab174163 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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