APC Anti-CSF-1-R antibody [AFS98] (ab210247)
Key features and details
- APC Rat monoclonal [AFS98] to CSF-1-R
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
APC Anti-CSF-1-R antibody [AFS98]
See all CSF-1-R primary antibodies -
Description
APC Rat monoclonal [AFS98] to CSF-1-R -
Host species
Rat -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Positive control
- Flow Cyt: Mouse C57Bl/6 peripheral blood cells.
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General notes
The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
ab210247 was purified from tissue culture supernatant via affinity chromatography. -
Clonality
Monoclonal -
Clone number
AFS98 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab210247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
Suggested use 0.06 µg. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. Suggested use 0.06 µg. |
Target
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Function
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. -
Tissue specificity
Expressed in bone marrow and in differentiated blood mononuclear cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 12978 Mouse
- SwissProt: P09581 Mouse
- Unigene: 22574 Mouse
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Alternative names
- C FMS antibody
- CD 115 antibody
- CD115 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab210247 has been referenced in 1 publication.
- Mendel ZI et al. Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages. J Cell Sci 135:N/A (2022). PubMed: 35107133