Anti-CSGLCAT antibody (ab75050)
Key features and details
- Rabbit polyclonal to CSGLCAT
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CSGLCAT antibody -
Description
Rabbit polyclonal to CSGLCAT -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide derived from an internal sequence of human CSGLCAT.
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Positive control
- extracts from Jurkat cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab75050 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 86 kDa (predicted molecular weight: 86 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 86 kDa (predicted molecular weight: 86 kDa). |
Target
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Function
Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity. -
Tissue specificity
Ubiquitous. Highly expressed in placenta, small intestine and pancreas. -
Sequence similarities
Belongs to the chondroitin N-acetylgalactosaminyltransferase family. -
Cellular localization
Golgi apparatus > Golgi stack membrane. - Information by UniProt
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Database links
- Entrez Gene: 54480 Human
- Omim: 608037 Human
- SwissProt: Q9P2E5 Human
- Unigene: 647084 Human
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Alternative names
- Chondroitin glucuronyltransferase antibody
- Chondroitin polymerizing factor 2 antibody
- Chondroitin sulfate glucuronyltransferase antibody
see all
Images
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All lanes : Anti-CSGLCAT antibody (ab75050) at 1/500 dilution
Lane 1 : extracts from Jurkat cells
Lane 2 : extracts from Jurkat cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 86 kDa
Observed band size: 86 kDa
Additional bands at: 50 kDa, 65 kDa. We are unsure as to the identity of these extra bands.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab75050 has been referenced in 2 publications.
- Wei L et al. Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling. FASEB J 34:16581-16600 (2020). PubMed: 33089528
- Lin R et al. The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells. Mol Cell 69:923-937.e8 (2018). PubMed: 29547721