Anti-CSRP1 antibody (ab70010)
Key features and details
- Rabbit polyclonal to CSRP1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CSRP1 antibody
See all CSRP1 primary antibodies -
Description
Rabbit polyclonal to CSRP1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide (Human) from an internal region
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Positive control
- IHC-P: Human brain tissue. WB: HeLa, HepG2, COLO, Jurkat cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab70010 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
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IHC-P |
1/50 - 1/100.
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa). |
IHC-P
1/50 - 1/100. |
Target
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Function
Could play a role in neuronal development. -
Sequence similarities
Contains 2 LIM zinc-binding domains. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 1465 Human
- Entrez Gene: 29276 Rat
- Omim: 123876 Human
- SwissProt: P21291 Human
- SwissProt: P47875 Rat
- Unigene: 108080 Human
- Unigene: 108075 Rat
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Alternative names
- CRP 1 antibody
- CRP antibody
- CRP1 antibody
see all
Images
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immunohistochemical analysis of paraffin embedded human brain tissue using ab70010 at 1/50 dilution. Right panel was treated with immunising peptide.
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All lanes : Anti-CSRP1 antibody (ab70010) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : HepG2 cell extract
Lane 3 : COLO cell extract
Lane 4 : Jurkat cell extract
Lane 5 : HeLa cell extract with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 21 kDa
Observed band size: 21 kDa
Additional bands at: 33 kDa, 50 kDa, 80 kDa. We are unsure as to the identity of these extra bands.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab70010 has been referenced in 5 publications.
- Yuan FY et al. Tanshinone IIA improves diabetes mellitus via the NF-?B-induced AMPK signal pathway. Exp Ther Med 16:4225-4231 (2018). PubMed: 30344697
- Kamar A et al. A Novel Role forCSRP1in a Lebanese Family with Congenital Cardiac Defects. Front Genet 8:217 (2017). PubMed: 29326753
- Heidersbach A et al. microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife 2:e01323 (2013). WB ; Mouse . PubMed: 24252873
- Järvinen PM et al. Cysteine-rich protein 1 is regulated by transforming growth factor-ß1 and expressed in lung fibrosis. J Cell Physiol 227:2605-12 (2012). WB ; Human . PubMed: 21882188
- Meves A et al. Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. Proc Natl Acad Sci U S A 108:15213-8 (2011). WB, ICC/IF ; Mouse . PubMed: 21876123