Key features and details
- Mouse monoclonal [2230C1a] to CTDSP2
- Suitable for: WB, Dot blot
- Reacts with: Human
- Isotype: IgG2b
Product nameAnti-CTDSP2 antibody [2230C1a]
See all CTDSP2 primary antibodies
DescriptionMouse monoclonal [2230C1a] to CTDSP2
Tested applicationsSuitable for: WB, Dot blotmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to near the N terminal amino acids 21-124 of Human CTDSP2
- recombinant human CTDSP2 fragment
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityProtein G purified
Purification notesab50621 was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
Our Abpromise guarantee covers the use of ab50621 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100. Detects a band of approximately 35 kDa (predicted molecular weight: 31 kDa).|
FunctionPreferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Tissue specificityExpression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
Sequence similaritiesContains 1 FCP1 homology domain.
- Information by UniProt
- Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- conserved gene amplified in osteosarcoma 4 antibody
Anti-CTDSP2 antibody [2230C1a] (ab50621) + recombinant CTDSP2 fragment
Predicted band size: 31 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
ab50621 has not yet been referenced specifically in any publications.