Product nameAnti-CTDSP2 antibody [OTI7F5]
See all CTDSP2 primary antibodies
DescriptionMouse monoclonal [OTI7F5] to CTDSP2
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant full length protein corresponding to Human CTDSP2 aa 1-271.
MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHV GQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQG RICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFL RRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYV KDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIP IFEELSGAEDVYTSLGQLRAP
Database link: O14595
- IHC-P: Human ovary adenocarcinoma tissue. WB: pCMV6-ENTRY CTDSP2 cDNA transfected HEK-293T cell lysate.
Clone OTI7F5 (formerly 7F5).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA, 50% Glycerol
Concentration information loading...
Purification notesPurified from cell culture supernatant.
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
Our Abpromise guarantee covers the use of ab236379 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Predicted molecular weight: 31 kDa.|
Heat-induced epitope retrieval by 1 mM EDTA in 10 mM Tris buffer (pH 8.5) at 120°C for 3 minutes.
FunctionPreferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Tissue specificityExpression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
Sequence similaritiesContains 1 FCP1 homology domain.
- Information by UniProt
- Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- conserved gene amplified in osteosarcoma 4 antibody
Paraffin-embedded human ovary adenocarcinoma tissue stained for CTDSP2 with ab236379 at a 1/150 dilution in immunohistochemical analysis.
All lanes : Anti-CTDSP2 antibody [OTI7F5] (ab236379) at 1/2000 dilution
Lane 1 : pCMV6-ENTRY control cDNA transfected HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
Lane 2 : pCMV6-ENTRY CTDSP2 cDNA transfected HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
Lysates/proteins at 5 µg per lane.
Predicted band size: 31 kDa
ab236379 has not yet been referenced specifically in any publications.