Key features and details
- Rabbit polyclonal to CTGF - Carboxyterminal end
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-CTGF antibody - Carboxyterminal end
See all CTGF primary antibodies
DescriptionRabbit polyclonal to CTGF - Carboxyterminal end
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment corresponding to Human CTGF (C terminal). E. coli-expressed human CTGF (C-terminal portion, 98 amino acids)
Database link: P29279
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 30% Glycerol, 0.5% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab59681 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 13 kDa (predicted molecular weight: 38 kDa).|
FunctionMajor connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Tissue specificityExpressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Sequence similaritiesBelongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.
Cellular localizationSecreted > extracellular space > extracellular matrix. Secreted.
- Information by UniProt
- CCN 2 antibody
- CCN family member 2 antibody
- CCN2 antibody
All lanes : Anti-CTGF antibody - Carboxyterminal end (ab59681) at 0.5 µg/ml
Lane 1 : recombinant human CTGF at 1 µg
Lane 2 : recombinant human CTGF at 0.25 µg
Lane 3 : recombinant human CTGF at 0.05 µg
Lane 4 : recombinant human CTGF at 0.01 µg
Predicted band size: 38 kDa
Observed band size: 13 kDa why is the actual band size different from the predicted?
ab59681 has been referenced in 2 publications.
- Cui S et al. CXCL8 Antagonist Improves Diabetic Nephropathy in Male Mice With Diabetes and Attenuates High Glucose-Induced Mesangial Injury. Endocrinology 158:1671-1684 (2017). PubMed: 28387853
- Bae WK et al. The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration. FASEB J 29:1653-62 (2015). IHC-P ; Mouse . PubMed: 25477280