CTOP, mu opioid receptor antagonist (ab120417)
Key features and details
- Potent, selective μ opioid receptor antagonist
- CAS Number: 103429-31-8
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
CTOP, mu opioid receptor antagonist -
Description
Potent, selective μ opioid receptor antagonist -
Biological description
Potent and highly selective μ opioid receptor antagonist (Kd = 1.1 nM).
-
General notes
>95% purity by HPLC. Specific analysis results available upon request.
-
CAS Number
103429-31-8 -
Chemical structure
Properties
-
Molecular weight
1062.27 -
Molecular formula
C50H67N11O11S2 -
Sequence
FCYWXTXT (Modifications: C-terminal amide; X-5 = Orn; X-7 = Pen; Phe-1 = D-Phe; Trp-4 = D-Trp; Disulfide bonds: 2-7) -
PubChem identifier
2884 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
-
Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120417 has been referenced in 1 publication.
- Wang Z et al. Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition. Brain 144:665-681 (2021). PubMed: 33367648