Recombinant
RabMAb

Recombinant Anti-CTP synthase/CTPS antibody [EPR8086(B)] (ab133743)

Overview

  • Product name

    Anti-CTP synthase/CTPS antibody [EPR8086(B)]
    See all CTP synthase/CTPS primary antibodies
  • Description

    Rabbit monoclonal [EPR8086(B)] to CTP synthase/CTPS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    corresponding to Human CTP synthase/CTPS aa 250-350.
    Database link: P17812

  • Positive control

    • Raji, HepG2, HeLa, U87-MG cell lysate; Raji cells
  • General notes

     

     

     This product was previously labelled as CTP synthase

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Relevance

      CTP synthase (CTPS) catalyzes the ATP-dependent conversion of UTP to CTP using either L-glutamine or ammonia as the source of nitrogen. The enzyme is important in the biosynthesis nucleic acids. It has a key role in cell growth, development, and tumorigenesis.
    • Cellular localization

      Cytosol, membrane
    • Database links

    • Alternative names

      • CTP synthase 1 antibody
      • CTP synthase antibody
      • CTP synthetase 1 antibody
      • CTP synthetase antibody
      • CTPS antibody
      • Cytidine 5 prime triphosphate synthetase antibody
      • Cytidine 5' triphosphate synthetase antibody
      • IMD24 antibody
      • UTP ammonia ligase 1 antibody
      see all

    Images

    • All lanes : Anti-CTP synthase/CTPS antibody [EPR8086(B)] (ab133743) at 1/1000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : U87-MG cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size: 67 kDa
      Observed band size: 67 kDa

    • Flow cytometry analysis of permeabilized Raji cells labelling CTP synthase/CTPS with ab133743 at 1/10 (red), with rabbit IgG negative control (green).

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Schafer S  et al. Translational regulation shapes the molecular landscape of complex disease phenotypes. Nat Commun 6:7200 (2015). WB . Read more (PubMed: 26007203) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133743.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up