Overview

  • Product name

    Anti-CTPS2 antibody - C-terminal
    See all CTPS2 primary antibodies
  • Description

    Rabbit polyclonal to CTPS2 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Horse, Cat, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide within Human CTPS2 aa 536-586 (C terminal). The exact sequence is proprietary.
    Sequence:

    PSPPY LGLLLAATGN LNAYLQQGCK LSSSDRYSDA SDDSFSEPRI AELEIS


    Database link: Q9NRF8

  • Positive control

    • HeLa and 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab190462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 65 kDa.
IP Use at 2-10 µg/mg of lysate.

Target

  • Function

    Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
  • Pathway

    Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.
  • Sequence similarities

    Belongs to the CTP synthase family.
    Contains 1 glutamine amidotransferase type-1 domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • CTP synthase 2 antibody
    • CTP synthase II antibody
    • CTP synthetase 2 antibody
    • CTPS2 antibody
    • CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2 antibody
    • FLJ43358 antibody
    • MGC32997 antibody
    • PYRG2_HUMAN antibody
    • UTP--ammonia ligase 2 antibody
    see all

Images

  • Immunoprecipitation analysis of 293T cell lysate (in NETN buffer, 1 mg per IP reaction; 20% of IP loaded) labeling CTPS2 using ab190462 at 6 μg per reaction (lane 1). A Control IgG was used in lane 2. For blotting immunoprecipitated CTPS2, ab190462 was used at 1 μg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

  • All lanes : Anti-CTPS2 antibody - C-terminal (ab190462) at 0.4 µg/ml

    Lane 1 : HeLa whole cell lysate in NETN buffer
    Lane 2 : 293T whole cell lysate in NETN buffer
    Lane 3 : Jurkat whole cell lysate in NETN buffer

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 65 kDa


    Exposure time: 3 minutes

References

ab190462 has not yet been referenced specifically in any publications.

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