Overview

  • Product name
    Anti-CTTNBP2 antibody - N-terminal
  • Description
    Rabbit polyclonal to CTTNBP2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CTTNBP2 aa 79-108 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8WZ74

  • Positive control
    • NCI-H460 cell line lysates; Human skeletal muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab174877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 181 kDa.

Target

  • Relevance
    This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton. CTTNBP2 regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance
  • Cellular localization
    Cytoplasmic
  • Database links
  • Alternative names
    • C7orf8 antibody
    • Cortactin binding protein 2 antibody
    • CORTBP2 antibody
    • Orf4 antibody

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skeletal muscle tissue labeling CTTNBP2 with ab174877 at 1/50 dilution. Detection utilised peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-CTTNBP2 antibody - N-terminal (ab174877) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Predicted band size: 181 kDa

References

ab174877 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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