Overview

  • Product name

    Curvularin, Antibiotic agent
  • Description

    Antibiotic agent. JAK signal inhibitor.
  • Biological description

    Antibiotic agent. Janus tyrosine kinase (JAK) signal inhibitor. Cell division inhibitor. AChE inhibitor. Inhibits iNOS and NOSII expression. Shows antibacterial, antifungal and antiprotozoal effects. Shows anti-inflammatory effects in vivo.
  • Purity

    > 95%
  • CAS Number

    10140-70-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Schmidt N  et al. The anti-inflammatory fungal compound (S)-curvularin reduces proinflammatory gene expression in an in vivo model of rheumatoid arthritis. J Pharmacol Exp Ther 343:106-14 (2012). Read more (PubMed: 22767531) »
  • Elzner S  et al. Inhibitors of inducible NO synthase expression: total synthesis of (S)-curvularin and its ring homologues. ChemMedChem 3:924-39 (2008). Read more (PubMed: 18366037) »
  • Vesonder RF  et al. Curvularin from penicillium baradicum Baghdadi NRRL 3754, and biological effects. J Environ Sci Health B 11:289-71 (1976). Read more (PubMed: 1002951) »

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