Overview

  • Product name
    Anti-Cx 37 / GJA4 antibody
    See all Cx 37 / GJA4 primary antibodies
  • Description
    Sheep polyclonal to Cx 37 / GJA4
  • Host species
    Sheep
  • Specificity
    Does not cross react with Connexins 40, 43 or 45.
  • Tested applications
    Suitable for: ICC/IFmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Hamster, Human
  • Immunogen

    Synthetic peptide corresponding to Rat Cx 37/ GJA4 aa 266-281.
    Sequence:

    YLPMGEGPSSPPCPTY

  • Positive control
    • Cos-7 cells transfected with cDNA encoding GJA4.
  • General notes

    Previously labelled as Connexin 37 / GJA4.

Properties

Applications

Our Abpromise guarantee covers the use of ab16587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.

Target

  • Function
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  • Tissue specificity
    Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
  • Sequence similarities
    Belongs to the connexin family. Alpha-type (group II) subfamily.
  • Cellular localization
    Cell membrane. Cell junction > gap junction.
  • Information by UniProt
  • Database links
  • Alternative names
    • Connexin 37 antibody
    • Connexin-37 antibody
    • Cx37 antibody
    • CXA4_HUMAN antibody
    • Gap junction alpha 4 protein antibody
    • Gap junction alpha-4 protein antibody
    • gap junction protein, alpha 4 37kDa (connexin 37) antibody
    • gap junction protein, alpha 4, 37kD (connexin 37) antibody
    • Gap junction protein, alpha 4, 37kDa antibody
    • Gja4 antibody
    • OTTHUMP00000004181 antibody
    • OTTHUMP00000004182 antibody
    see all

References

ab16587 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

Thank you for contacting us and your interest in our products.
The antibody you are interested in, the anti-Connexin 37 / GJA4 antibody (ab16587), has been raised against an immunogen taken from the rat protein. This immunogen shares 100% homology with the mouse protein and the antibody would therefore be expected to be able to detect the mouse protein. However, as we have not tried it ourselves I would not be able to guarantee this.
We are unfortunately unable to offer free samples of any of our products. This is due to the logistics that this would involve. We do however have a testing discount scheme which may interest you.
This offer means that if you purchase ab16587 as usual, test the antibody with your mouse protein and let us know of the results through an Abreview (no matter whether positive or negative) you would be eligible for a free primary antibody of your choice from our catalogue. More information on this offer can be found here: www.abcam.com/collaborationdiscount
The only constraint of this offer is that the antibody to be tested needs to be purchased, tested and the free antibody claimed within 4 months. If you would be interested in participating in this scheme please do let me know as a discount code needs to be issued prior to the purchase of ab16587.
I hope this information has been of help. If you require any further information please do not hesitate to contact us again.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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