Key features and details
- Rat monoclonal [7F17] to CX3CL1
- Suitable for: Neutralising, WB
- Reacts with: Mouse
- Isotype: IgG2
Product nameAnti-CX3CL1 antibody [7F17]
See all CX3CL1 primary antibodies
DescriptionRat monoclonal [7F17] to CX3CL1
Tested applicationsSuitable for: Neutralising, WBmore details
Species reactivityReacts with: Mouse
Recombinant fragment corresponding to Mouse CX3CL1 aa 25-336. Extracellular domain
QHLGMTKCEIMCDKMTSRIPVALLIRYQLNQESCGKRAIVLETTQHRRFC ADPKEKWVQDAMKHLDHQAAALTKNGGKFEKRVDNVTPGITLATRGLSPS ALTKPESATLEDLALELTTISQEARGTMGTSQEPPAAVTGSSLSTSEAQD AGLTAKPQSIGSFEAADISTTVWPSPAVYQSGSSSWAEEKATESPSTTAP SPQVSTTSPSTPEENVGSEGQPPWVQGQDLSPEKSLGSEEINPVHTDNFQ ERGPGNTVHPSVAPISSEETPSPELVASGSQAPKIEEPIHATADPQKLSV LITPVPDTQAAT
Database link: O35188
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituent: 100% PBS
Concentration information loading...
PurityProtein A/G purified
Our Abpromise guarantee covers the use of ab194599 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Neutralising||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 42 kDa.|
FunctionThe soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Tissue specificitySmall intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Sequence similaritiesBelongs to the intercrine delta family.
modificationsA soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
O-glycosylated with core 1 or possibly core 8 glycans.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- A 152E5.2 antibody
- AB030188 antibody
- ABCD 3 antibody
ab194599 has not yet been referenced specifically in any publications.