Key features and details
- Mouse monoclonal [MM0207-8J23] to CX3CL1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG1
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab89229 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 42 kDa.|
|IHC-P||1/20 - 1/100. Antigen retrieval is not essential but may optimise staining.|
FunctionThe soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Tissue specificitySmall intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Sequence similaritiesBelongs to the intercrine delta family.
modificationsA soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
O-glycosylated with core 1 or possibly core 8 glycans.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- A 152E5.2 antibody
- AB030188 antibody
- ABCD 3 antibody
ab89229 has been referenced in 1 publication.
- Nebiker CA et al. GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer. Clin Cancer Res 20:3094-106 (2014). Human . PubMed: 24737547