Anti-CX3CR1 antibody (ab217291)

Rabbit polyclonal CX3CR1 antibody. Validated in WB, IHC, Flow Cyt and tested in Mouse, Rat. Immunogen corresponding to synthetic peptide.

Overview

  • Product name

  • Description

    Rabbit polyclonal to CX3CR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human CX3CR1 aa 216-230 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    QTLFS CKNHKKAKAI


    Database link: P49238

  • Positive control

    • WB - Rat brain lysate, Mouse heart lysate. IHC-P - Mouse lymph tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab217291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 40 kDa).
Flow Cyt 1/100.

Target

  • Function

    Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
  • Tissue specificity

    Expressed in lymphoid and neural tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta chemokine receptor-like 1 antibody
    • C X3 C CKR 1 antibody
    • C-X3-C CKR-1 antibody
    • CCRL1 antibody
    • Chemokine C X3 C motif receptor 1 antibody
    • CMK BRL 1 antibody
    • CMK-BRL-1 antibody
    • CMK-BRL1 antibody
    • CMKBLR1 antibody
    • CMKDR1 antibody
    • CX3C chemokine receptor 1 antibody
    • CX3C CKR1 antibody
    • CX3C1_HUMAN antibody
    • CX3CR1 antibody
    • Fractalkine receptor antibody
    • G-protein coupled receptor 13 antibody
    • GPR13 antibody
    • GPRV28 antibody
    • V28 antibody
    see all

Images

  • Flow Cytometry of Mouse Spleen with ab217310 at 1/100
  • All lanes : Anti-CX3CR1 antibody (ab217291) at 1/200 dilution

    Lane 1 : Rat brain lysate
    Lane 2 : Mouse heart lysate

    Secondary
    All lanes : Anti-Rabbit HRP conjugated antibody at 1/3000 dilution

    Predicted band size: 40 kDa
    Observed band size: 39 kDa
    why is the actual band size different from the predicted?



    12% Gel

  • Immunohistochemical analysis of paraformaldehyde fixed, paraffin embedded Mouse lymph tissue labeling CX3CR1 with ab217291 at 1/500 dilution.

References

ab217291 has not yet been referenced specifically in any publications.

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