Question (3633) | CX3CR1 peptide (ab8124)

Go to datasheet (ab8124)

Question

Does this peptide block the binding of fractalkine to it's receptor? Also, do the related polyclonal antibodies ab8020, ab8021, or ab7201 block binding to or inhibit chemotazis mediated by fractalkine? thank you for your help Kristen M. Heers

Answer

This peptide blocks the binding of the antibody -- Rabbit polyclonal to human CX3CR1 (extracellular) ab8020 -- to human CX3CR1. There is no evidence that this peptide blocks the binding of fractalkine to its receptor (i.e. binding of fractalkine to CX3CR1). With regard to the other polyclonal antibodies that you mention, again there is no evidence that they block binding to or inhibit chemotazis mediated by fractalkine

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