Overview

  • Product name

  • Description

    Rabbit polyclonal to CXCL16
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 52-193 of Human CXCL16 (AAH17588).

  • Positive control

    • A549, HepG2 whole cell lysate (ab7900)

Properties

Applications

Our Abpromise guarantee covers the use of ab101404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/500. Antigen retrieval is recommended using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (pH: 8.0)

Target

  • Function

    Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • Tissue specificity

    Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • Sequence similarities

    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • Database links

  • Alternative names

    • C-X-C motif chemokine 16 antibody
    • Chemokine (C X C motif) ligand 16 antibody
    • Chemokine, CXC motif, ligand 16 antibody
    • CXC chemokine ligand 16 antibody
    • Cxcl16 antibody
    • CXCLG16 antibody
    • CXL16_HUMAN antibody
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
    • SCYB16 antibody
    • Small inducible cytokine B16 precursor antibody
    • Small-inducible cytokine B16 antibody
    • SR-PSOX antibody
    • SRPSOX antibody
    • Transmembrane chemokine CXCL16 antibody
    • UNQ2759/PRO6714 antibody
    see all

Images

  • Anti-CXCL16 antibody (ab101404) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 28 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded H661 xenograft, using ab101404 at 1/100 dilution.

References

This product has been referenced in:

  • Mei J  et al. CXCL16/CXCR6 interaction Promotes Endometrial Decidualization via the PI3K/ AKT Pathway. Reproduction N/A:N/A (2019). Read more (PubMed: 30620718) »
  • Wang M & Liu R CXCL16 protects against oxygen and glucose deprivation-induced injury in human microvascular endothelial cells-1: Potential role in ischemic stroke. J Cell Physiol N/A:N/A (2019). Read more (PubMed: 30945283) »
See all 12 Publications for this product

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