Overview

  • Product name

  • Description

    Rabbit polyclonal to CXCL16
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human CXCL16 aa 154-204.
    Sequence:

    PVGSLSSDKELTRPNETTIHTAGHSLAAGPEAGENQKQPEKNAGPTARTS A


    Database link: Q9H2A7

  • Positive control

    • CACO-2 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab220616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
Recommended conditions:
Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function

    Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • Tissue specificity

    Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • Sequence similarities

    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • Database links

  • Alternative names

    • C-X-C motif chemokine 16 antibody
    • Chemokine (C X C motif) ligand 16 antibody
    • Chemokine, CXC motif, ligand 16 antibody
    • CXC chemokine ligand 16 antibody
    • Cxcl16 antibody
    • CXCLG16 antibody
    • CXL16_HUMAN antibody
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
    • SCYB16 antibody
    • Small inducible cytokine B16 precursor antibody
    • Small-inducible cytokine B16 antibody
    • SR-PSOX antibody
    • SRPSOX antibody
    • Transmembrane chemokine CXCL16 antibody
    • UNQ2759/PRO6714 antibody
    see all

Images

  • Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized CACO-2 cells labeling CXCL16 with ab220616 at 4 μg/ml (green).

References

ab220616 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab220616.
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