Key features and details
- Rabbit polyclonal to CXCL1/GRO alpha
- Suitable for: WB, Sandwich ELISA, Neutralising
- Reacts with: Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Constituent: 100% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab194657 was purified by affinity chromatography employing immobilized CXCL1/GRO alpha matrix.
Our Abpromise guarantee covers the use of ab194657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/0.1 - 1/0.2. Predicted molecular weight: 11 kDa.|
|Sandwich ELISA||Use a concentration of 0.5 - 2 µg/ml.
ab194657 in conjunction with an compatible secondary reagent as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant CXCR2.
|Neutralising||Use a concentration of 1.5 - 3 µg/ml.|
FunctionHas chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
modificationsN-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
- Information by UniProt
- C-X-C motif chemokine 1 antibody
- Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody
- chemokine (C-X-C motif) ligand 1 antibody
ab194657 has not yet been referenced specifically in any publications.