Overview

  • Product name

    Anti-CXCL7/PBP antibody [EPR7767]
    See all CXCL7/PBP primary antibodies
  • Description

    Rabbit monoclonal [EPR7767] to CXCL7/PBP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    corresponding to Human CXCL7/PBP aa 50-150.
    Database link: P02775

  • Positive control

    • Human platelet lysate
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Previously labelled as CXCL7. 

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 14 kDa.
  • Application notes
    Is unsuitable for IHC-P.
  • Target

    • Function

      LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications

      Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)).
      Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor.
      NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils.
      NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • B TG1 antibody
      • Beta TG antibody
      • Beta thromboglobulin antibody
      • Beta-TG antibody
      • C-X-C motif chemokine 7 antibody
      • Chemokine (C X C motif) ligand 7 antibody
      • Connective tissue activating peptide III antibody
      • CTAP 3 antibody
      • CTAP III antibody
      • CTAP-III antibody
      • CTAP-III(1-81) antibody
      • CTAP3 antibody
      • CTAPIII antibody
      • CXC chemokine ligand 7 antibody
      • CXCL 7 antibody
      • CXCL7 antibody
      • CXCL7_HUMAN antibody
      • LA PF 4 antibody
      • LA-PF4 antibody
      • LDGF antibody
      • Leukocyte derived growth factor antibody
      • Leukocyte-derived growth factor antibody
      • Low-affinity platelet factor IV antibody
      • Macrophage-derived growth factor antibody
      • MDGF antibody
      • NAP 2 antibody
      • NAP-2 antibody
      • NAP-2(1-63) antibody
      • NAP-2(1-66) antibody
      • NAP-2(73) antibody
      • NAP-2(74) antibody
      • Neutrophil activating peptide 2 antibody
      • Neutrophil-activating peptide 2(1-63) antibody
      • PBP antibody
      • Platelet basic protein antibody
      • PPBP antibody
      • Pro platelet basic protein (chemokine (C-X-C motif) ligand 7) antibody
      • Pro platelet basic protein antibody
      • SCYB7 antibody
      • Small inducible cytokine subfamily B member 7 antibody
      • Small-inducible cytokine B7 antibody
      • TC1 antibody
      • TC2 antibody
      • TGB antibody
      • TGB1 antibody
      • THBGB antibody
      • THBGB1 antibody
      • Thrombocidin 1 antibody
      • Thrombocidin 2 antibody
      • Thromboglobulin, beta-1 antibody
      see all

    Images

    • Anti-CXCL7/PBP antibody [EPR7767] (ab133252) at 1/1000 dilution + Human platelet lysate at 10 µg

      Predicted band size: 14 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab133252 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133252.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up