Overview

  • Product name
    Anti-CXCR1 antibody
    See all CXCR1 primary antibodies
  • Description
    Rabbit polyclonal to CXCR1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the N terminus of Human CXCR1 (NP_000625).

  • Positive control
    • Human fetal skin lysate; Human fetal tonsil tissue.

Properties

  • Form
    Lyophilised:Reconstitute in 200:micro;l of sterile H2O.
    The lyophilized antibody is stable for at least one year when stored at -20ºC after reconstitution.
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 98% PBS, 1% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 40 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • C C antibody
      • C C CKR 1 antibody
      • C-X-C chemokine receptor type 1 antibody
      • CCCKR1 antibody
      • CD 181 antibody
      • CD128 antibody
      • CD181 antibody
      • CD181 antigen antibody
      • CDw128a antibody
      • Chemokine (C X C motif) receptor 1 antibody
      • Chemokine (C X C) receptor 1 antibody
      • Chemokine receptor 1 antibody
      • CKR 1 antibody
      • CMKAR1 antibody
      • CXC-R1 antibody
      • CXCR 1 antibody
      • CXCR-1 antibody
      • CXCR1 antibody
      • CXCR1_HUMAN antibody
      • High affinity interleukin 8 receptor A antibody
      • High affinity interleukin-8 receptor A antibody
      • IL 8 receptor type 1 antibody
      • IL 8R A antibody
      • IL-8 receptor type 1 antibody
      • IL-8R A antibody
      • IL8 receptor antibody
      • IL8 receptor type 1 antibody
      • IL8R1 antibody
      • IL8RA antibody
      • IL8RBA antibody
      • Interleukin 8 receptor alpha antibody
      • Interleukin 8 receptor type 1 antibody
      • Interleukin 8 receptor type A antibody
      see all

    Images

    • Western blot - Anti-CXCR1 antibody (ab124344)
      Western blot - Anti-CXCR1 antibody (ab124344)
      Anti-CXCR1 antibody (ab124344) at 1/500 dilution + Human fetal skin lysate.

      Predicted band size: 40 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR1 antibody (ab124344)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR1 antibody (ab124344)
      ab124344, at 1/100 dilution, staining CXCR1 in formalin-fixed, paraffin-embedded Human fetal tonsil tissue.

    References

    This product has been referenced in:

    See 1 Publication for this product

    Publishing research using ab124344? Please let us know so that we can cite the reference in this datasheet.

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