• Product name
  • Description
    Rabbit polyclonal to CXCR1
  • Host species
  • Tested applications
    Suitable for: WB, IP, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Monkey
  • Immunogen

    Synthetic peptide (C terminal).

  • General notes
    Please note this antibody is now raised in Rabbit. Concentration varies from batch to batch, usually 0.5 mg/ml to 0.7 mg/ml.



Our Abpromise guarantee covers the use of ab14936 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 42 kDa.
IP 1/250.
IHC-Fr Use at an assay dependent concentration. PubMed: 20505763


  • Function
    Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C antibody
    • C C CKR 1 antibody
    • C-X-C chemokine receptor type 1 antibody
    • CCCKR1 antibody
    • CD 181 antibody
    • CD128 antibody
    • CD181 antibody
    • CD181 antigen antibody
    • CDw128a antibody
    • Chemokine (C X C motif) receptor 1 antibody
    • Chemokine (C X C) receptor 1 antibody
    • Chemokine receptor 1 antibody
    • CKR 1 antibody
    • CMKAR1 antibody
    • CXC-R1 antibody
    • CXCR 1 antibody
    • CXCR-1 antibody
    • CXCR1 antibody
    • CXCR1_HUMAN antibody
    • High affinity interleukin 8 receptor A antibody
    • High affinity interleukin-8 receptor A antibody
    • IL 8 receptor type 1 antibody
    • IL 8R A antibody
    • IL-8 receptor type 1 antibody
    • IL-8R A antibody
    • IL8 receptor antibody
    • IL8 receptor type 1 antibody
    • IL8R1 antibody
    • IL8RA antibody
    • IL8RBA antibody
    • Interleukin 8 receptor alpha antibody
    • Interleukin 8 receptor type 1 antibody
    • Interleukin 8 receptor type A antibody
    see all


  • ab14936 staining CXCR1 in rat whole hippocampus tissue by Immunohistochemistry (Frozen sections). After fixation in 4% PFA in PBS (pH 7.4), brains were cryoprotected in 30% sucrose in PBS at +4°C, frozen, and thereafter kept at -80°C until used. For the immunostaining, brains were cryosectioned in 30 µm slices, collected in PBS (pH 7.4), and processed in a free-floating system. Slices were first incubated in the blocking solution (BS) containing 2% bovine serum albumin, 2% goat serum, and 0.1% Triton X-100 in PBS (pH 7.4) for 1 hour at room temperature, and thereafter with the primary antibody for 24–48 hours at +4°C in BS at a 1/1000 dilution. After washing in PBS, slices were incubated with an Alexa 568 secondary antibody at a 1/2000 dilution.


This product has been referenced in:
  • Laurén HB  et al. Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats. PLoS One 5:e10733 (2010). IHC-Fr ; Rat . Read more (PubMed: 20505763) »

See 1 Publication for this product

Customer reviews and Q&As

Thank you for contacting us.
We currently only have available the one size listed on the datasheet for a particular antibody. We do not have any CXCR antibody panels at this time.

I hope this information is helpful to you. Please do not...

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Thank you for your phone call. I have contacted the originator of ab14936 and there have not been any complaints regarding the second batch that you received. I am going to send you a vial from the newest batch of ab14936 that the supplier has, free of...

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Thank you for your enquiry regarding ab14936 and ab14935. The ab14936 and 14935 both have antibodies to Keyhole limpet hemocyanin, a protien that is phylogenetically very distant from mammalian species. We have not seen any cross reactivity of KLH ant...

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Thanks again for your email. I was able to get the following information from the originator of ab14936 regarding the use of the antibody in Western blotting. If you have any more questions, please contact us again. Dimerization and oligomerization...

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At times we have seen dimerization of G-protein coupled receptor in various systems including dopamine D2 receptor (Farooqui et. al., 1991 and Sakata et al., 1992). The glycosylation and other post-translational modifications also causes significant s...

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Thank you very much for your email. We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not work as specified on the datasheet, we will offer a replacement or reimbursement. If you...

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