Key features and details
- Mouse monoclonal [MM0222-7J40] to CXCR2
- Suitable for: IHC-Fr, Neutralising, Flow Cyt
- Reacts with: Human
- Isotype: IgG2a
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein G purified
Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
Our Abpromise guarantee covers the use of ab89254 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||1/20 - 1/100.|
|Neutralising||Use at an assay dependent concentration.|
|Flow Cyt||1/50 - 1/200.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionReceptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
modificationsPhosphorylated upon ligand binding; which is required for desensitization.
Cellular localizationCell membrane.
- Information by UniProt
- C-X-C chemokine receptor type 2 antibody
- CD 182 antibody
- CD182 antibody
ab89254 has not yet been referenced specifically in any publications.