Product nameAnti-CXCR3 antibody
See all CXCR3 primary antibodies
DescriptionRabbit polyclonal to CXCR3
Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
Species reactivityReacts with: Human
Synthetic peptide, from internal sequence amino acids of Human CXCR3.
- Human brain (cortex neurons) tissue; K562 cell extract.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
Note: PBS (without Mg2+, Ca2+)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab133420 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 40 kDa.|
|IHC-P||Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionReceptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC).
Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). May play a role in angiogenesis.
Isoform 3 mediates the activity of CXCL11.
Tissue specificityIsoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- C-X-C chemokine receptor type 3 antibody
- CD 183 antibody
- CD182 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain (cortex neurons) tissue labelling CXCR3 with ab133 antibody at 10µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
All lanes : Anti-CXCR3 antibody (ab133420) at 1/500 dilution
Lane 1 : K562 cell extract
Lane 2 : K562 cell extract with synthesized peptide
Predicted band size: 40 kDa
ab133420 has not yet been referenced specifically in any publications.