Key features and details
- Rabbit polyclonal to CXXC4
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CXXC4 antibody
See all CXXC4 primary antibodies
DescriptionRabbit polyclonal to CXXC4
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide of 18 amino acids near the N terminal end of Human CXXC4 (NP_079488).
- Human brain tissue lysate
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. The product can be stored for up to 12 months.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab105400 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 21 kDa.|
FunctionActs as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.
Sequence similaritiesContains 1 CXXC-type zinc finger.
- Information by UniProt
- CXXC finger 4 antibody
- CXXC finger protein 4 antibody
- CXXC type zinc finger protein 4 antibody
Immunofluorescence of CXXC4 in Human brain tissue with ab105400 at 20ug/mL.
Immunohistochemistry of CXXC4 in Human brain tissue with ab105400 at 10 μg/mL.
All lanes : Anti-CXXC4 antibody (ab105400) at 1 µg/ml
Lane 1 : Human brain tissue lysate
Lane 2 : Human brain tissue lysate with CXXC4 peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 21 kDa
ab105400 has been referenced in 2 publications.
- Lu J et al. MiR-629-5p promotes colorectal cancer progression through targetting CXXC finger protein 4. Biosci Rep 38:N/A (2018). PubMed: 30042169
- Kojima T et al. Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling. Oncogene 28:297-305 (2009). PubMed: 18931698