Key features and details
- Rabbit polyclonal to CXXC5
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-CXXC5 antibody
See all CXXC5 primary antibodies
DescriptionRabbit polyclonal to CXXC5
Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Synthetic peptide, 15 aa from near the amino terminus of human CXXC5 (NP_057547).
- Human brain tissue lysate.
Predicted to not cross-react with other CXXC protein family members.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Primary antibody notesPredicted to not cross-react with other CXXC protein family members.
Our Abpromise guarantee covers the use of ab106533 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa|
FunctionMay indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells.
Sequence similaritiesContains 1 CXXC-type zinc finger.
Cellular localizationNucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.
- Information by UniProt
FormThere are 2 isoforms produced by alternative splicing.
- CF5 antibody
- CXXC finger 5 protein antibody
- CXXC finger protein 5 antibody
ab106533 has been referenced in 2 publications.
- Yasar P et al. Estradiol-Estrogen Receptor a Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway. Sci Rep 6:37808 (2016). WB ; Human . PubMed: 27886276
- Kim HY et al. CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation. FASEB J 28:615-26 (2014). WB ; Mouse . PubMed: 24136587