• Product name
  • Description
    Rabbit polyclonal to CXXC5
  • Host species
  • Tested applications
    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, 15 aa from near the amino terminus of human CXXC5 (NP_057547).

  • Positive control
    • Human brain tissue lysate.
  • General notes

    Predicted to not cross-react with other CXXC protein family members.



Our Abpromise guarantee covers the use of ab106533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa
ICC Use a concentration of 2.5 µg/ml.


  • Function
    May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells.
  • Sequence similarities
    Contains 1 CXXC-type zinc finger.
  • Cellular localization
    Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.
  • Information by UniProt
  • Database links
  • Form
    There are 2 isoforms produced by alternative splicing.
  • Alternative names
    • CF5 antibody
    • CXXC finger 5 protein antibody
    • CXXC finger protein 5 antibody
    • CXXC-type zinc finger protein 5 antibody
    • CXXC5 antibody
    • CXXC5_HUMAN antibody
    • HSPC195 antibody
    • Putative MAPK-activating protein PM08 antibody
    • Putative NF-kappa-B-activating protein 102 antibody
    • retinoid-inducible nuclear factor antibody
    • RINF antibody
    • TCCCIA00297 antibody
    • WID antibody
    • WT1-induced Inhibitor of Dishevelled antibody
    see all


  • Anti-CXXC5 antibody (ab106533) at 1 µg/ml + human brain tissue lysate at 15 µg/ml

    Predicted band size: 33 kDa

  • Immunohistochemistry of CXXC5 in human brain tissue with ab106533 at 2.5 µg/ml.
  • Immunofluorescence of CXXC5 in Human Brain cells using ab106533 at 20 ug/ml.


This product has been referenced in:
  • Yasar P  et al. Estradiol-Estrogen Receptor a Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway. Sci Rep 6:37808 (2016). WB ; Human . Read more (PubMed: 27886276) »
  • Kim HY  et al. CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation. FASEB J 28:615-26 (2014). WB ; Mouse . Read more (PubMed: 24136587) »

See all 2 Publications for this product

Customer reviews and Q&As

I have placed an order for you, however the antibody is currently out of stock; we are expecting it to be in stock on 17th July and will then be dispatched.

Please quote the order number "1122106" to our customer service team for any...

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Sorry! there was a typos error; the correct abID I am suggest is ab133191

Thank you very much for your patience.

We unfortunately do not have new lot for this product at the moment however lab has agreed to retest the lot; I will share the results with you soon.

In order to keep you going with your research...

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Thank you very much for having patience!

I have requested the exact immunogen information from our collaborator and is now waiting a reply from them. I will send you the details soon.

Currently, we do not have explanation for 120 kDa ...

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Thank you very much for providing the protocol details and images.

The protocol seems fine to me however the following protocol optimizations could;

- At Abcam we use 5% BSA for blocking; I would recommend trying BSA instead of milk.<...

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Thank you very much for sending the details. I have sent an email to my colleague in lab and requested new QC data for this lot. I will contact you with the explanation soon.

Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

I am at...

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