Cyanine3 alkyne, Yellow emitting fluorescent dye (ab146444)

Overview

  • Product name

    Cyanine3 alkyne, Yellow emitting fluorescent dye
  • Description

    Yellow emitting fluorescent alkyne dye.
  • Alternative names

    • 3,3-Dimethyl-1-[6-oxo-6-(prop-2-ynylamino)hexyl]-2-[(1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-enyl]-3H-indolium chloride
    • alkyne-Cy3
    • Cy3 alkyne
  • Biological description

    Yellow emitting fluorescent alkyne dye for click chemistry reactions. Analog of Cy3® alkyne. Can be attached to nearly any molecule bearing an azide group. Non water-soluble. When used with organic co-solvent (DMSO or DMF), can be efficiently attached to water-soluble molecules such as proteins, or peptides.

  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    555nm
  • Emission

    570nm
  • Chemical name

    3,3-Dimethyl-1-[6-oxo-6-(prop-2-ynylamino)hexyl]-2-[(1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-enyl]-3H-indolium chloride
  • Molecular weight

    530.14
  • Molecular formula

    C33H40ClN3O
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Vanparijs N  et al. Transiently responsive protein-polymer conjugates via a 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators. Chem Commun (Camb) 51:13972-5 (2015). Read more (PubMed: 26242974) »
  • Burnham-Marusich AR  et al. Size-matched alkyne-conjugated cyanine fluorophores to identify differences in protein glycosylation. Electrophoresis 35:2621-5 (2014). Read more (PubMed: 24931120) »
  • Hatzenpichler R  et al. In situ visualization of newly synthesized proteins in environmental microbes using amino acid tagging and click chemistry. Environ Microbiol 16:2568-90 (2014). Read more (PubMed: 24571640) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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