Cyanine5 amine, Red emitting fluorescent dye (ab146463)

Overview

  • Product name

    Cyanine5 amine, Red emitting fluorescent dye
  • Description

    Photostable, red emitting fluorescent dye with a free amino group.
  • Alternative names

    • Cy5 amine
  • Biological description

    Photostable, red emitting fluorescent dye with a free amino group for reaction with activated esters and activated carboxy groups. Analog of Cy5® amine.

  • Purity

    > 95%
  • General notes

    Moderate solubility in water.

  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    646nm
  • Emission

    662nm
  • Chemical name

    1-[6-(6-aminohexylamino)-6-oxohexyl]-3,3-dimethyl-2-[(1E,3E,5E)-5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dienyl]-3H-indolium chloride hydrochloride
  • Molecular weight

    653.77
  • Molecular formula

    C38H53ClN4O.HCl
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in water, in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Hartley JM  et al. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. J Control Release 231:50-9 (2016). Read more (PubMed: 26855050) »
  • Yang J  et al. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. J Control Release 218:36-44 (2015). Read more (PubMed: 26410808) »
  • Zhang R  et al. Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates. Proc Natl Acad Sci U S A 111:12181-6 (2014). Read more (PubMed: 25092316) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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