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Rabbit polyclonal to Cyclin
Recombinant fragment containing a sequence corresponding to a region within amino acids 1-377 of Human Cyclin.
HCT116 whole cell lysate, Human RF48 xenograft tissue
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 79% PBS, 20% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 43 kDa.
1/100 - 1/1000.
The cell cycle is regulated by the interplay of many molecules. Key among these are the cyclins which are expressed and then degraded in a concerted fashion to drive the stages of the cell cycle. Cyclins combine with cyclin dependent kinases (cdks) to form activated kinases that phosphorylate targets leading to cell cycle regulation. A breakdown in the regulation of this cycle can lead to out of control growth and contribute to tumor formation. Defects in many of the molecules that regulate the cell cycle have been implicated in cancer
Cyclin 1 antibody
Western blot - Anti-Cyclin antibody (ab152116)
Anti-Cyclin antibody (ab152116) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg
Predicted band size: 43 kDa 10% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cyclin antibody (ab152116)
Immunohistochemical analysis of paraffin-embedded Human RF48 xenograft tissue labeling Cyclin using ab152116 at a 1/500 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"