Recombinant
RabMAb

Recombinant Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175)

Publishing research using ab134175? Please let us know so that we can cite the reference in this datasheet.

ab134175 has been referenced in 300 publications.

  • Zhao W  et al. Long noncoding RNA NSCLCAT1 increases non-small cell lung cancer cell invasion and migration through the Hippo signaling pathway by interacting with CDH1. FASEB J 33:1151-1166 (2019). PubMed: 30148675
  • Luo Y  et al. Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/ß-catenin signaling pathway. Cancer Lett 440-441:11-22 (2019). PubMed: 30312725
  • Shi Z  et al. Silibinin inhibits endometrial carcinoma via blocking pathways of STAT3 activation and SREBP1-mediated lipid accumulation. Life Sci 217:70-80 (2019). PubMed: 30452972
  • Ji Q  et al. Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis. Nat Commun 10:313 (2019). PubMed: 30659184
  • Gao Y  et al. LXRa Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/ß-catenin Signaling. J Cancer 10:156-167 (2019). PubMed: 30662536
  • Su W  et al. Long non-coding RNA highly up-regulated in liver cancer promotes epithelial-to-mesenchymal transition process in oral squamous cell carcinoma. J Cell Mol Med 23:2645-2655 (2019). PubMed: 30677230
  • Su W  et al. Circular RNA hsa_circ_0007059 indicates prognosis and influences malignant behavior via AKT/mTOR in oral squamous cell carcinoma. J Cell Physiol N/A:N/A (2019). PubMed: 30680715
  • Fang F  et al. Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro. Onco Targets Ther 12:685-697 (2019). PubMed: 30705597
  • Chen Y  et al. Lost expression of cell adhesion molecule 1 is associated with bladder cancer progression and recurrence and its overexpression inhibited tumor cell malignant behaviors. Oncol Lett 17:2047-2056 (2019). PubMed: 30719104
  • Zhang Y  et al. Chinese Herbal Medicine Wenxia Changfu Formula Reverses Cell Adhesion-Mediated Drug Resistance via the Integrin ß1-PI3K-AKT Pathway in Lung Cancer. J Cancer 10:293-304 (2019). PubMed: 30719123
  • Li Z  et al. GDNF family receptor alpha 2 promotes neuroblastoma cell proliferation by interacting with PTEN. Biochem Biophys Res Commun 510:339-344 (2019). PubMed: 30722993
  • Yifan T  et al. Hepatic regeneration by associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is feasible but attenuated in rat liver with thioacetamide-induced fibrosis. Surgery 165:345-352 (2019). PubMed: 30249433
  • Qiao E  et al. Long noncoding RNA TALNEC2 plays an oncogenic role in breast cancer by binding to EZH2 to target p57KIP2 and involving in p-p38 MAPK and NF-?B pathways. J Cell Biochem 120:3978-3988 (2019). PubMed: 30378143
  • Wang J  et al. CD151 promotes proliferation and migration of SK-NEP-1 cells via the GSK-3ß/P21/cyclinD signaling pathway. Pathol Res Pract 215:329-334 (2019). PubMed: 30578155
  • Zhou X  et al. Sialylation of MUC4ß N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight 4:N/A (2019). PubMed: 30730306
  • Ren J  et al. microRNA-758 inhibits the malignant phenotype of osteosarcoma cells by directly targeting HMGA1 and deactivating the Wnt/ß-catenin pathway. Am J Cancer Res 9:36-52 (2019). PubMed: 30755810
  • Wang M  et al. miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3. Sci Rep 9:2032 (2019). PubMed: 30765768
  • Wei W  et al. miR-600 inhibits lung cancer via downregulating the expression of METTL3. Cancer Manag Res 11:1177-1187 (2019). PubMed: 30774445
  • Wang Y  et al. A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis. Mol Cancer 18:28 (2019). PubMed: 30782188
  • Qi M  et al. CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4. Oncogenesis 8:23 (2019). PubMed: 30872583
  • Zhao F  et al. MicroRNA-133b suppresses bladder cancer malignancy by targeting TAGLN2-mediated cell cycle. J Cell Physiol 234:4910-4923 (2019). PubMed: 30317571
  • Liu Y  et al. The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer. Onco Targets Ther 12:1815-1824 (2019). PubMed: 30881034
  • Johnson J  et al. Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers. PLoS One 14:e0209392 (2019). PubMed: 30875375
  • Fang G  et al. LncRNA MRAK048635_P1 is critical for vascular smooth muscle cell function and phenotypic switching in essential hypertension. Biosci Rep 39:N/A (2019). PubMed: 30833363
  • Molina L  et al. mTOR inhibition affects Yap1-ß-catenin-induced hepatoblastoma growth and development. Oncotarget 10:1475-1490 (2019). PubMed: 30863496
  • Yang Z  et al. The biological function of long noncoding RNA FAL1 in oesophageal carcinoma cells. Artif Cells Nanomed Biotechnol 47:896-903 (2019). PubMed: 30873881
  • Sun C  et al. URG11 promotes proliferation and induced apoptosis of LNCaP cells. Int J Mol Med 43:2075-2085 (2019). PubMed: 30864678
  • Hou Y  et al. Genetic ablation of TAZ induces HepG2 liver cancer cell apoptosis through activating the CaMKII/MIEF1 signaling pathway. Onco Targets Ther 12:1765-1779 (2019). PubMed: 30881030
  • Shao G  et al. lncRNA CASC9 positively regulates CHK1 to promote breast cancer cell proliferation and survival through sponging the miR-195/497 cluster. Int J Oncol 54:1665-1675 (2019). PubMed: 30816435
  • Song J  et al. LATS2 overexpression attenuates the therapeutic resistance of liver cancer HepG2 cells to sorafenib-mediated death via inhibiting the AMPK-Mfn2 signaling pathway. Cancer Cell Int 19:60 (2019). PubMed: 30923462
  • Xu J  et al. Knockdown of serpin peptidase inhibitor clade C member 1 inhibits the growth of nasopharyngeal carcinoma cells. Mol Med Rep 19:3658-3666 (2019). PubMed: 30896875
  • Fernández-Martos S  et al. Sustained Human Hair Follicle Growth Ex Vivo in a Glycosaminoglycan Hydrogel Matrix. Int J Mol Sci 20:N/A (2019). PubMed: 30970537
  • Wang K  et al. IL1RN mediates the suppressive effect of methionine deprivation on glioma proliferation. Cancer Lett 454:146-157 (2019). PubMed: 30978442
  • Zhang J  et al. Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy. Biomed Pharmacother 114:108844 (2019). PubMed: 30981108
  • Yang Q  et al. MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. Arthritis Res Ther 21:97 (2019). PubMed: 30987676
  • Xu K  et al. LncRNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma through epigenetically silencing CDKN1B(p27) via EZH2. Exp Cell Res 380:198-204 (2019). PubMed: 31004581
  • Gu Y  et al. Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca2+]i and mitochondrial fission/fusion. Chem Biol Interact 307:63-72 (2019). PubMed: 31009640
  • Yao W  et al. Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway. Cancer Cell Int 19:97 (2019). PubMed: 31011291
  • Zhao Y  et al. MicroRNA-103 promotes nasopharyngeal carcinoma through targeting TIMP-3 and the Wnt/ß-catenin pathway. Laryngoscope N/A:N/A (2019). PubMed: 31038780
  • Wang G  et al. Intraductal fulvestrant for Therapy of ERa-positive Ductal Carcinoma in Situ (DCIS) of the breast- a Preclinical Study. Carcinogenesis N/A:N/A (2019). PubMed: 31046118
  • Tan ZB  et al. Rheum palmatum extract exerts anti-hepatocellular carcinoma effects by inhibiting signal transducer and activator of transcription 3 signaling. J Ethnopharmacol 232:62-72 (2019). PubMed: 30553869
  • Gan S  et al. Knockdown of ZFAS1 suppresses the progression of acute myeloid leukemia by regulating microRNA-150/Sp1 and microRNA-150/Myb pathways. Eur J Pharmacol 844:38-48 (2019). PubMed: 30502345
  • Zhang L  et al. Cytokine augments the sorafenib-induced apoptosis in Huh7 liver cancer cell by inducing mitochondrial fragmentation and activating MAPK-JNK signalling pathway. Biomed Pharmacother 110:213-223 (2019). PubMed: 30476722
  • Sun WL  et al. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. Biosci Rep 39:N/A (2019). PubMed: 30498093
  • Farshadi E  et al. The positive circadian regulators CLOCK and BMAL1 control G2/M cell cycle transition through Cyclin B1. Cell Cycle 18:16-33 (2019). PubMed: 30558467
  • Duan G  et al. Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR-34a/cyclin D1 axis. Int J Oncol 54:17-28 (2019). PubMed: 30365098
  • Sun Y  et al. Restoration of miRNA-148a in pancreatic cancer reduces invasion and metastasis by inhibiting the Wnt/ß-catenin signaling pathway via downregulating maternally expressed gene-3. Exp Ther Med 17:639-648 (2019). PubMed: 30651845
  • Yang X  et al. Nonylphenol promotes the proliferation of colorectal cancer COLO205 cells by upregulating the expression of protein kinase C ?. Oncol Lett 17:2498-2506 (2019). PubMed: 30675313
  • Li X  et al. Knock-Down of HOXB8 Prohibits Proliferation and Migration of Colorectal Cancer Cells via Wnt/ß-Catenin Signaling Pathway. Med Sci Monit 25:711-720 (2019). PubMed: 30677006
  • Zhang H  et al. MicroRNA-1258, regulated by c-Myb, inhibits growth and epithelial-to-mesenchymal transition phenotype via targeting SP1 in oral squamous cell carcinoma. J Cell Mol Med 23:2813-2821 (2019). PubMed: 30734471
  • Wen Q  et al. FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signaling. EBioMedicine 40:198-209 (2019). PubMed: 30738830
  • Zhang X  et al. Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression. Braz J Med Biol Res 52:e7994 (2019). PubMed: 30810622
  • Feng SQ  et al. VEGF Antagonism Attenuates Cerebral Ischemia/Reperfusion-Induced Injury via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis. Biol Pharm Bull 42:692-702 (2019). PubMed: 30828041
  • Zhang L  et al. FLOT1 promotes tumor development, induces epithelial-mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma. Thorac Cancer 10:909-917 (2019). PubMed: 30838797
  • Sun X  et al. Inhibition of NET-1 suppresses proliferation and promotes apoptosis of hepatocellular carcinoma cells by activating the PI3K/AKT signaling pathway. Exp Ther Med 17:2334-2340 (2019). PubMed: 30867719
  • Sun L  et al. Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression. BMC Cancer 19:247 (2019). PubMed: 30890138
  • Song B  et al. LncRNA ENST00000539653 acts as an oncogenic factor via MAPK signalling in papillary thyroid cancer. BMC Cancer 19:297 (2019). PubMed: 30940124
  • Xie X  et al. Fe3O4-solamargine induces apoptosis and inhibits metastasis of pancreatic cancer cells. Int J Oncol 54:905-915 (2019). PubMed: 30483763
  • Li Y  et al. Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway. BMC Cancer 18:1230 (2018). PubMed: 30526546
  • Yang R  et al. LASP2 suppressed malignancy and Wnt/ß-catenin signaling pathway activation in bladder cancer. Exp Ther Med 16:5215-5223 (2018). PubMed: 30542477
  • Sun H & Gao D Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372. BMC Cancer 18:1252 (2018). PubMed: 30547768
  • Xiao S & Zhu H Leucine-Rich Alpha-2-Glycoprotein1 Gene Interferes with Regulation of Apoptosis in Leukemia KASUMI-1 Cells. Med Sci Monit 24:8348-8356 (2018). PubMed: 30455412
  • Wang S  et al. miR-124 regulates STAT3-mediated cell proliferation, migration and apoptosis in bladder cancer. Oncol Lett 16:5875-5881 (2018). PubMed: 30344738
  • Xu J  et al. Knockdown of LETM1 inhibits proliferation and metastasis of human renal cell carcinoma cells. Oncol Lett 16:6377-6382 (2018). PubMed: 30405774
  • Tao Y  et al. Huaier Augmented the Chemotherapeutic Sensitivity of Oxaliplatin via Downregulation of YAP in Hepatocellular Carcinoma. J Cancer 9:3962-3970 (2018). PubMed: 30410600
  • Mizoguchi A  et al. MicroRNA-8073: Tumor suppressor and potential therapeutic treatment. PLoS One 13:e0209750 (2018). PubMed: 30589909
  • Wang C  et al. MiR-3188 Inhibits Non-small Cell Lung Cancer Cell Proliferation Through FOXO1-Mediated mTOR-p-PI3K/AKT-c-JUN Signaling Pathway. Front Pharmacol 9:1362 (2018). PubMed: 30618730
  • He Q  et al. Tsantan Sumtang Alleviates Chronic Hypoxia-Induced Pulmonary Hypertension by Inhibiting Proliferation of Pulmonary Vascular Cells. Biomed Res Int 2018:9504158 (2018). PubMed: 30622966
  • Wang Y  et al. Myosin Heavy Chain 10 (MYH10) Gene Silencing Reduces Cell Migration and Invasion in the Glioma Cell Lines U251, T98G, and SHG44 by Inhibiting the Wnt/ß-Catenin Pathway. Med Sci Monit 24:9110-9119 (2018). PubMed: 30552850
  • Zhang S  et al. Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition. Front Physiol 9:1650 (2018). PubMed: 30524310
  • Xu DH  et al. Transmembrane protein GRINA modulates aerobic glycolysis and promotes tumor progression in gastric cancer. J Exp Clin Cancer Res 37:308 (2018). PubMed: 30541591
  • Wohlrab C  et al. The Association Between Ascorbate and the Hypoxia-Inducible Factors in Human Renal Cell Carcinoma Requires a Functional Von Hippel-Lindau Protein. Front Oncol 8:574 (2018). PubMed: 30555801
  • Zhang F  et al. HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-ß/smad signaling pathway in cervical carcinoma cells. Cancer Cell Int 18:204 (2018). PubMed: 30559605
  • Wei S & Wang H Ligustrazine promoted hypoxia-treated cell growth by upregulation of miR-135b in human umbilical vein endothelial cells. Exp Mol Pathol 106:102-108 (2018). PubMed: 30576641
  • Tang CT  et al. RAB31 Targeted by MiR-30c-2-3p Regulates the GLI1 Signaling Pathway, Affecting Gastric Cancer Cell Proliferation and Apoptosis. Front Oncol 8:554 (2018). PubMed: 30534536
  • Ding J  et al. Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma. BMB Rep 51:630-635 (2018). PubMed: 30293547
  • Li L  et al. GTPBP4 Promotes Gastric Cancer Progression via Regulating P53 Activity. Cell Physiol Biochem 45:667-676 (2018). PubMed: 29408813
  • Haller M  et al. 16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A 115:E1849-E1858 (2018). PubMed: 29432158
  • Li F  et al. CEP55 promotes cell proliferation and inhibits apoptosis via the PI3K/Akt/p21 signaling pathway in human glioma U251 cells. Oncol Lett 15:4789-4796 (2018). PubMed: 29552118
  • Zhao C  et al. C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. Oncogene 37:4821-4837 (2018). PubMed: 29773900
  • Tao ZW & Zou PA Adenovirus-mediated small interfering RNA targeting ezrin induces apoptosis and inhibits metastasis of human osteosarcoma MG-63 cells. Biosci Rep 38:N/A (2018). PubMed: 29899165
  • Han W  et al. HBx gene transfection affects the cycle of primary renal tubular epithelial cells through regulating cyclin expression. Mol Med Rep 18:1947-1954 (2018). PubMed: 29956780
  • Yuan Y  et al. Proliferative role of BDNF/TrkB signaling is associated with anoikis resistance in cervical cancer. Oncol Rep 40:621-634 (2018). PubMed: 29989647
  • Li Y  et al. Overexpression of KLF5 inhibits puromycin-induced apoptosis of podocytes. Mol Med Rep 18:3843-3849 (2018). PubMed: 30106142
  • Sun X  et al. microRNA-761 regulates glycogen synthase kinase 3ß expression and promotes the proliferation and cell cycle of human gastric cancer cells. Oncol Lett 16:3459-3464 (2018). PubMed: 30127949
  • Wang S  et al. Expression of KIAA1456 in lung cancer tissue and its effects on proliferation, migration and invasion of lung cancer cells. Oncol Lett 16:3791-3795 (2018). PubMed: 30127990
  • Li N  et al. MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2). Med Sci Monit 24:5960-5972 (2018). PubMed: 30147110
  • Li XF  et al. Downregulation of the long noncoding RNA MBNL1-AS1 protects sevoflurane-pretreated mice against ischemia-reperfusion injury by targeting KCNMA1. Exp Mol Med 50:115 (2018). PubMed: 30185781
  • Sriraman A  et al. CDK4 inhibition diminishes p53 activation by MDM2 antagonists. Cell Death Dis 9:918 (2018). PubMed: 30206211
  • Zhang J  et al. miRNA-218 regulates the proliferation and apoptosis of cervical cancer cells via targeting Gli3. Exp Ther Med 16:2433-2441 (2018). PubMed: 30210595
  • Yao J  et al. Long noncoding RNA TOB1-AS1, an epigenetically silenced gene, functioned as a novel tumor suppressor by sponging miR-27b in cervical cancer. Am J Cancer Res 8:1483-1498 (2018). PubMed: 30210918
  • Zhang C  et al. FOXA1 is upregulated in glioma and promotes proliferation as well as cell cycle through regulation of cyclin D1 expression. Cancer Manag Res 10:3283-3293 (2018). PubMed: 30233244
  • Li L  et al. Smokeless tobacco extract inhibits proliferation and promotes apoptosis in oral mucous fibroblasts. Oncol Lett 16:5066-5074 (2018). PubMed: 30250574
  • Jieensinue S  et al. Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways. BMC Cell Biol 19:21 (2018). PubMed: 30253740
  • Gong L  et al. Astragaloside IV Protects Rat Cardiomyocytes from Hypoxia-Induced Injury by Down-Regulation of miR-23a and miR-92a. Cell Physiol Biochem 49:2240-2253 (2018). PubMed: 30257251
  • Liu Z  et al. Long noncoding RNA neuroblastoma-associated transcript 1 gene inhibits malignant cellular phenotypes of bladder cancer through miR-21/SOCS6 axis. Cell Death Dis 9:1042 (2018). PubMed: 30310053
  • Zhou LJ  et al. Erinacine Facilitates the Opening of the Mitochondrial Permeability Transition Pore Through the Inhibition of the PI3K/ Akt/GSK-3ß Signaling Pathway in Human Hepatocellular Carcinoma. Cell Physiol Biochem 50:851-867 (2018). PubMed: 30355923
  • Zheng X  et al. MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts. Braz J Med Biol Res 51:e7574 (2018). PubMed: 30365725
  • Leng X  et al. Low-intensity pulsed ultrasound promotes proliferation and migration of HaCaT keratinocytes through the PI3K/AKT and JNK pathways. Braz J Med Biol Res 51:e7862 (2018). PubMed: 30365726
  • Zhang M  et al. A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. Nat Commun 9:4475 (2018). PubMed: 30367041
  • Ding H  et al. Silencing of Xeroderma Pigmentosum Group D Gene Promotes Hepatoma Cell Growth by Reducing P53 Expression. Med Sci Monit 24:8015-8021 (2018). PubMed: 30409962
  • Chen L  et al. Nuclear factor-kappa B-dependent X-box binding protein 1 signalling promotes the proliferation of nucleus pulposus cells under tumour necrosis factor alpha stimulation. Cell Prolif N/A:e12542 (2018). PubMed: 30430692
  • Qian W  et al. CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer. Int J Oncol 53:2021-2033 (2018). PubMed: 30226575
  • Bugaj LJ  et al. Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science 361:N/A (2018). PubMed: 30166458
  • Wan J  et al. Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways. Cancer Cell Int 18:165 (2018). PubMed: 30377412
  • He D  et al. Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) is Underexpressed in Clear Cell Renal Cell Carcinoma Tissue and Transfection and Overexpression in Caki-1 Cells Inhibits Cell Proliferation and Increases Apoptosis. Med Sci Monit 24:8391-8400 (2018). PubMed: 30459299
  • Ding X  et al. IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway. Cancer Cell Int 18:176 (2018). PubMed: 30459526
  • Chen M  et al. Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-?B pathway. Pharmacol Res 139:273-285 (2018). PubMed: 30471409
  • Zhao B  et al. Peiminine Inhibits Glioblastoma in Vitro and in Vivo Through Cell Cycle Arrest and Autophagic Flux Blocking. Cell Physiol Biochem 51:1566-1583 (2018). PubMed: 30497066
  • Qian J  et al. Tanshinone IIA promotes IL2-mediated SW480 colorectal cancer cell apoptosis by triggering INF2-related mitochondrial fission and activating the Mst1-Hippo pathway. Biomed Pharmacother 108:1658-1669 (2018). PubMed: 30372868
  • Xu X  et al. Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling. Med Sci Monit 24:8064-8073 (2018). PubMed: 30415267
  • Wang G  et al. Upregulation of mtSSB by interleukin-6 promotes cell growth through mitochondrial biogenesis-mediated telomerase activation in colorectal cancer. Int J Cancer N/A:N/A (2018). PubMed: 30415472
  • Zhang X  et al. Downregulation of NLRP2 inhibits HUVEC viability by inhibiting the MAPK signaling pathway. Mol Med Rep N/A:N/A (2018). PubMed: 30431084
  • Luo X  et al. Bioinformatics analysis of microarray profiling identifies the mechanism of focal adhesion kinase signalling pathway in proliferation and apoptosis of breast cancer cells modulated by green tea polyphenol epigallocatechin 3-gallate. J Pharm Pharmacol 70:1606-1618 (2018). PubMed: 30187481
  • Kan SF  et al. Sulforaphane regulates apoptosis- and proliferation-related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer. Int J Mol Med 42:2447-2458 (2018). PubMed: 30226534
  • Luo L  et al. MiR-124-3p suppresses glioma aggressiveness via targeting of Fra-2. Pathol Res Pract 214:1825-1834 (2018). PubMed: 30243808
  • Tao W  et al. Haploinsufficiency of Insm1 Impairs Postnatal Baseline ß-Cell Mass. Diabetes 67:2615-2625 (2018). PubMed: 30257979
  • Liu J  et al. Sirtuin-1 protects hair follicle stem cells from TNFa-mediated inflammatory stress via activating the MAPK-ERK-Mfn2 pathway. Life Sci 212:213-224 (2018). PubMed: 30292830
  • Han W & Liu J LncRNA-p21 inhibited the proliferation of osteosarcoma cells via the miR-130b/PTEN/AKT signaling pathway. Biomed Pharmacother 97:911-918 (2018). WB . PubMed: 29136769
  • Wang D  et al. MiR-182 promotes prostate cancer progression through activating Wnt/ß-catenin signal pathway. Biomed Pharmacother 99:334-339 (2018). WB . PubMed: 29353209
  • Chen Z  et al. HBO1 promotes cell proliferation in bladder cancer via activation of Wnt/ß-catenin signaling. Mol Carcinog 57:12-21 (2018). PubMed: 28796367
  • Zhang J  et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature 553:91-95 (2018). PubMed: 29160310
  • Liu F  et al. Molecular mechanisms of Ellis-van Creveld gene variations in ventricular septal defect. Mol Med Rep 17:1527-1536 (2018). PubMed: 29257216
  • Li KP  et al. Upregulation of miR-598 promotes cell proliferation and cell cycle progression in human colorectal carcinoma by suppressing INPP5E expression. Mol Med Rep 17:2991-2997 (2018). PubMed: 29257251
  • Zheng W & Yu A EZH2-mediated suppression of lncRNA-LET promotes cell apoptosis and inhibits the proliferation of post-burn skin fibroblasts. Int J Mol Med 41:1949-1957 (2018). PubMed: 29393360
  • Rychahou P  et al. Colorectal cancer lung metastasis treatment with polymer-drug nanoparticles. J Control Release 275:85-91 (2018). PubMed: 29421609
  • Liu H  et al. Sodium fluoride causes hepatocellular S-phase arrest by activating ATM-p53-p21 and ATR-Chk1-Cdc25A pathways in mice. Oncotarget 9:4318-4337 (2018). PubMed: 29435105
  • Li YJ  et al. Target therapy of TRIM-14 inhibits osteosarcoma aggressiveness through the nuclear factor-?B signaling pathway. Exp Ther Med 15:2365-2373 (2018). PubMed: 29467844
  • Kong X  et al. Increased Expression of the YPEL3 Gene in Human Colonic Adenocarcinoma Tissue and the Effects on Proliferation, Migration, and Invasion of Colonic Adenocarcinoma Cells In Vitro via the Wnt/b-Catenin Signaling Pathway. Med Sci Monit 24:4767-4775 (2018). PubMed: 29988027
  • Jin J  et al. miR-448 targets Rab2B and is pivotal in the suppression of pancreatic cancer. Oncol Rep 40:1379-1389 (2018). PubMed: 30015954
  • Chen J  et al. Colony stimulating factor-1 receptor promotes proliferation, migration and invasion in the human nasopharyngeal carcinoma 6-10B cell line via the phosphoinositide 3-kinase/Akt pathway. Oncol Lett 16:1205-1211 (2018). PubMed: 30061942
  • Xing Y  et al. TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway. Cell Commun Signal 16:43 (2018). PubMed: 30064446
  • Gupta A  et al. PAK2-c-Myc-PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect. Cell Death Dis 9:825 (2018). PubMed: 30068946
  • Chen SY  et al. MicroRNA-340 Inhibits Epithelial-Mesenchymal Transition by Impairing ROCK-1-Dependent Wnt/ß-Catenin Signaling Pathway in Epithelial Cells from Human Benign Prostatic Hyperplasia. Chin Med J (Engl) 131:2008-2012 (2018). PubMed: 30082536
  • Ji K  et al. TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway. Cancer Cell Int 18:117 (2018). PubMed: 30127666
  • Cui X  et al. MEG-3-mediated Wnt/ß-catenin signaling pathway controls the inhibition of tunicamycin-mediated viability in glioblastoma. Oncol Lett 16:2797-2804 (2018). PubMed: 30127865
  • Quan Wang J  et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem 33:1199-1211 (2018). PubMed: 30132373
  • Wang Y  et al. Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/ß-catenin signal pathway in hepatocellular carcinoma. Cell Death Dis 9:851 (2018). PubMed: 30154476
  • Prabakaran AD  et al. Identification of early indicators of altered metabolism in normal development using a rodent model system. Dis Model Mech 11:N/A (2018). PubMed: 29434026
  • Yu R  et al. miR-377 targets CUL4A and regulates metastatic capability in ovarian cancer. Int J Mol Med 41:3147-3156 (2018). PubMed: 29512715
  • Wang L  et al. TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway. Mol Med Rep 17:7017-7026 (2018). PubMed: 29568863
  • Wang Y  et al. Adipokine RBP4 drives ovarian cancer cell migration. J Ovarian Res 11:29 (2018). PubMed: 29642915
  • Sun M  et al. Targeted delivery of immuno-RNase may improve cancer therapy. Cancer Cell Int 18:58 (2018). PubMed: 29686536
  • Xu L  et al. Morphological adaptation of sheep's rumen epithelium to high-grain diet entails alteration in the expression of genes involved in cell cycle regulation, cell proliferation and apoptosis. J Anim Sci Biotechnol 9:32 (2018). PubMed: 29686866
  • Wang S  et al. SH2B1 promotes epithelial-mesenchymal transition through the IRS1/ß-catenin signaling axis in lung adenocarcinoma. Mol Carcinog 57:640-652 (2018). WB ; Human . PubMed: 29380446
  • Gao L  et al. Dual inhibition of mTORC1/2 by DCZ0358 induces cytotoxicity in multiple myeloma and overcomes the protective effect of the bone marrow microenvironment. Cancer Lett 421:135-144 (2018). WB . PubMed: 29428642
  • Park E  et al. Paljung-San, a traditional herbal medicine, attenuates benign prostatic hyperplasia in vitro and in vivo. J Ethnopharmacol 218:109-115 (2018). PubMed: 29501675
  • Li W  et al. Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells. Biomed Pharmacother 100:257-266 (2018). WB . PubMed: 29438839
  • Kleinsimon S  et al. GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway. Sci Rep 8:5750 (2018). WB . PubMed: 29636527
  • Guo M  et al. Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis. J Cell Mol Med 22:3202-3214 (2018). PubMed: 29566305
  • Yang J  et al. Novel NADPH oxidase inhibitor VAS2870 suppresses TGF-ß-dependent epithelial-to-mesenchymal transition in retinal pigment epithelial cells. Int J Mol Med 42:123-130 (2018). PubMed: 29620174
  • Hou GR  et al. Juglanin ameliorates UVB-induced skin carcinogenesis via anti-inflammatory and proapoptotic effects in vivo and in vitro. Int J Mol Med 42:41-52 (2018). PubMed: 29620254
  • Chen C  et al. LncRNA HULC mediates radioresistance via autophagy in prostate cancer cells. Braz J Med Biol Res 51:e7080 (2018). PubMed: 29694502
  • Li K  et al. Oldhamianoside II inhibits prostate cancer progression via regulation of EMT and the Wnt/ß-catenin signaling pathway. Oncol Lett 15:9457-9463 (2018). PubMed: 29805669
  • Liu X Up-regulation of miR-20a by HPV16 E6 exerts growth-promoting effects by targeting PDCD6 in cervical carcinoma cells. Biomed Pharmacother 102:996-1002 (2018). WB . PubMed: 29710555
  • Molina L  et al. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol 188:1895-1909 (2018). PubMed: 29920228
  • Cui Y & Yang S Overexpression of Annexin A1 protects against benzo[a]pyrene-induced bronchial epithelium injury. Mol Med Rep 18:349-357 (2018). PubMed: 29749523
  • Cao N  et al. MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/ß-catenin signaling. Biomed Pharmacother 106:483-490 (2018). PubMed: 29990836
  • Cummins CB  et al. Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway. Int J Mol Sci 19:N/A (2018). PubMed: 29795016
  • Long ZW  et al. MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway. Mol Cells 41:532-544 (2018). PubMed: 29902839
  • Cui C  et al. Targeting Orai1-mediated store-operated calcium entry by RP4010 for anti-tumor activity in esophagus squamous cell carcinoma. Cancer Lett 432:169-179 (2018). PubMed: 29908962
  • Cai L  et al. Naringin inhibits ovarian tumor growth by promoting apoptosis: An in vivo study. Oncol Lett 16:59-64 (2018). PubMed: 29928387
  • Pan H & Zhu L Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22. Biomed Pharmacother 106:225-231 (2018). PubMed: 29960169
  • Yang WH  et al. Heterogeneous nuclear ribonucleoprotein M promotes the progression of breast cancer by regulating the axin/ß-catenin signaling pathway. Biomed Pharmacother 105:848-855 (2018). PubMed: 30021377
  • Yu W  et al. Astragaloside IV reduces the hypoxia-induced injury in PC-12 cells by inhibiting expression of miR-124. Biomed Pharmacother 106:419-425 (2018). PubMed: 29990829
  • Mi B  et al. Icariin promotes wound healing by enhancing the migration and proliferation of keratinocytes via the AKT and ERK signaling pathway. Int J Mol Med 42:831-838 (2018). PubMed: 29767263
  • Huang S  et al. WAVE3 promotes proliferation, migration and invasion via the AKT pathway in pancreatic cancer. Int J Oncol 53:672-684 (2018). PubMed: 29845225
  • Cao Y  et al. LncRNA ATB promotes proliferation and metastasis in A549 cells by down-regulation of microRNA-494. J Cell Biochem 119:6935-6942 (2018). PubMed: 29693289
  • Lampert F  et al. The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation. Elife 7:N/A (2018). PubMed: 29911972
  • Liu X & Meng J Tanshinone IIA ameliorates lipopolysaccharide-induced inflammatory response in bronchial epithelium cell line BEAS-2B by down-regulating miR-27a. Biomed Pharmacother 104:158-164 (2018). PubMed: 29772436
  • Fu H  et al. Microarray analysis reveals Tmub1 as a cell cycle-associated protein in rat hepatocytes. Mol Med Rep 17:4337-4344 (2018). PubMed: 29344642
  • You S  et al. Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway. Mol Med Rep 17:4203-4212 (2018). PubMed: 29344654
  • Yan X  et al. Lup-20(29)-en-3ß,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria. Cell Death Dis 9:241 (2018). PubMed: 29445224
  • Meng X  et al. MicroRNA-125b-1-3p mediates intervertebral disc degeneration in rats by targeting teashirt zinc finger homeobox 3. Exp Ther Med 15:2627-2633 (2018). PubMed: 29456666
  • Huang Y  et al. High Expression of ITGA3 Promotes Proliferation and Cell Cycle Progression and Indicates Poor Prognosis in Intrahepatic Cholangiocarcinoma. Biomed Res Int 2018:2352139 (2018). PubMed: 29511671
  • Jiang H  et al. PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma. Cancer Med 7:869-882 (2018). WB . PubMed: 29441724
  • Zhu L  et al. TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/ß-catenin pathway. J Transl Med 16:7 (2018). PubMed: 29343267
  • Yu X  et al. Baicalein induces cervical cancer apoptosis through the NF-?B signaling pathway. Mol Med Rep 17:5088-5094 (2018). PubMed: 29393414
  • Wu Y  et al. Suv4-20h1 promotes G1 to S phase transition by downregulating p21WAF1/CIP1 expression in chronic myeloid leukemia K562 cells. Oncol Lett 15:6123-6130 (2018). PubMed: 29616094
  • Raab M  et al. PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells. Nat Commun 9:1106 (2018). PubMed: 29549256
  • Wu J  et al. miR-503 suppresses the proliferation and metastasis of esophageal squamous cell carcinoma by triggering autophagy via PKA/mTOR signaling. Int J Oncol N/A:N/A (2018). PubMed: 29568867
  • Jiang Y  et al. MAP30 promotes apoptosis of U251 and U87 cells by suppressing the LGR5 and Wnt/ß-catenin signaling pathway, and enhancing Smac expression. Oncol Lett 15:5833-5840 (2018). PubMed: 29556310
  • Xu L  et al. Rnf138 deficiency promotes apoptosis of spermatogonia in juvenile male mice. Cell Death Dis 8:e2795 (2017). IHC-P ; Mouse . PubMed: 28518149
  • Cao H  et al. Secondary bile acid-induced dysbiosis promotes intestinal carcinogenesis. Int J Cancer 140:2545-2556 (2017). PubMed: 28187526
  • Manier S  et al. Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma. Sci Transl Med 9:N/A (2017). PubMed: 28490664
  • Capurro M  et al. Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling. J Cell Biol 216:2911-2926 (2017). PubMed: 28696225
  • Yao CJ  et al. Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells. J Ginseng Res 41:247-256 (2017). PubMed: 28701864
  • Song R  et al. Maternal Sevoflurane Exposure Causes Abnormal Development of Fetal Prefrontal Cortex and Induces Cognitive Dysfunction in Offspring. Stem Cells Int 2017:6158468 (2017). PubMed: 29098009
  • Effenberger M  et al. Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation. Oncotarget 8:85858-85867 (2017). WB ; Human . PubMed: 29156762
  • Zhao X  et al. Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells. Oncol Lett 14:2177-2185 (2017). PubMed: 28789442
  • Ji Q  et al. miR-216a inhibits osteosarcoma cell proliferation, invasion and metastasis by targeting CDK14. Cell Death Dis 8:e3103 (2017). PubMed: 29022909
  • Wu VC  et al. The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes. Sci Rep 7:39121 (2017). WB ; Human . PubMed: 28102204
  • Lu T  et al. Adamts18 deficiency promotes colon carcinogenesis by enhancing ß-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer. Oncotarget 8:18979-18990 (2017). IHC ; Mouse . PubMed: 28145888
  • Zhang C  et al. Growth of tyrosine kinase inhibitor-resistant Philadelphia-positive acute lymphoblastic leukemia: Role of bone marrow stromal cells. Oncol Lett 13:2059-2070 (2017). WB . PubMed: 28454362
  • Tian L  et al. Siamese crocodile bile induces apoptosis in NCI-H1299 human non-small cell lung cancer cells via a mitochondria-mediated intrinsic pathway and inhibits tumorigenesis. Mol Med Rep 15:1727-1737 (2017). PubMed: 28259903
  • Yan L  et al. Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma. Int J Mol Med 39:1371-1380 (2017). WB ; Human . PubMed: 28440426
  • Wang T  et al. Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/ß-catenin signaling pathway. Oncotarget 8:18991-19012 (2017). WB ; Human . PubMed: 28177909
  • Yan KS  et al. Non-equivalence of Wnt and R-spondin ligands during Lgr5(+) intestinal stem-cell self-renewal. Nature 545:238-242 (2017). IHC-P ; Mouse . PubMed: 28467820
  • Ding L  et al. MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2. J Exp Clin Cancer Res 36:45 (2017). WB ; Human . PubMed: 28327189
  • Qiao B  et al. MicroRNA-27a-3p Modulates the Wnt/ß-Catenin Signaling Pathway to Promote Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Stem Cells by Targeting SFRP1. Sci Rep 7:44688 (2017). WB ; Human . PubMed: 28425477
  • Kapil S  et al. The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Oncotarget 8:26515-26531 (2017). WB . PubMed: 28460446
  • Sun L  et al. Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma. Cancer Sci 108:1338-1346 (2017). WB . PubMed: 28387999
  • Wang Q  et al. Compound anisodine affects the proliferation and calcium overload of hypoxia-induced rat retinal progenitor cells and brain neural stem cells via the p-ERK1/2/HIF-1a/VEGF pathway. Exp Ther Med 14:600-608 (2017). PubMed: 28672973
  • Peng T  et al. Centrosomal protein 55 activates NF-?B signalling and promotes pancreatic cancer cells aggressiveness. Sci Rep 7:5925 (2017). IHC . PubMed: 28724890
  • Fu S  et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep 7:43771 (2017). PubMed: 28256562
  • Li L  et al. siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells. Oncol Lett 13:3014-3024 (2017). PubMed: 28529558
  • Deshmukh A  et al. Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines. Sci Rep 7:2256 (2017). PubMed: 28536422
  • Kim JT  et al. Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells. Int J Oncol 50:2200-2206 (2017). PubMed: 28498396
  • Wang R  et al. Long noncoding RNA CASC2 predicts the prognosis of glioma patients and functions as a suppressor for gliomas by suppressing Wnt/ß-catenin signaling pathway. Neuropsychiatr Dis Treat 13:1805-1813 (2017). PubMed: 28744130
  • Wang S  et al. Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/ß-catenin signaling pathway. Sci Rep 7:6215 (2017). PubMed: 28740094
  • Ninomiya T  et al. Iron depletion is a novel therapeutic strategy to target cancer stem cells. Oncotarget 8:98405-98416 (2017). PubMed: 29228699
  • Zhang ZF  et al. MicroRNA-182 downregulates Wnt/ß-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9. Oncotarget 8:101345-101361 (2017). PubMed: 29254169
  • Shan L  et al. Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1. J Cancer 8:4087-4097 (2017). PubMed: 29187885
  • Jin D  et al. Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development inApcmin/+mice. Oncotarget 8:97787-97800 (2017). PubMed: 29228651
  • Wang C  et al. Krüppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling. Oncotarget 8:100358-100370 (2017). PubMed: 29245984
  • Chen DG  et al. Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter. J Exp Clin Cancer Res 36:186 (2017). PubMed: 29246166
  • Liu Y  et al. MicroRNA-193a-3p inhibits cell proliferation in prostate cancer by targeting cyclin D1. Oncol Lett 14:5121-5128 (2017). WB ; Human . PubMed: 29142597
  • Hou T  et al. CLCA4 inhibits bladder cancer cell proliferation, migration, and invasion by suppressing the PI3K/AKT pathway. Oncotarget 8:93001-93013 (2017). PubMed: 29190973
  • Fu S  et al. Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia. Oncotarget 8:88537-88551 (2017). PubMed: 29179455
  • He T  et al. Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis. Int J Oncol 51:1722-1730 (2017). PubMed: 29075788
  • Yang Y  et al. LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells. Oncotarget 8:84123-84139 (2017). PubMed: 29137410
  • Lv C  et al. MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists. Nat Commun 8:1036 (2017). PubMed: 29051494
  • Li FF  et al. Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway. Oncotarget 8:70854-70864 (2017). PubMed: 29050326
  • Liu Q  et al. Vascular endothelial growth receptor 1 acts as a stress-associated protein in the therapeutic response to thalidomide. Exp Ther Med 14:4263-4271 (2017). PubMed: 29075340
  • Liu L  et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol 37:N/A (2017). PubMed: 27956703
  • Zhang Y  et al. Involvement of Notch2 in all-trans retinoic acid-induced inhibition of mouse embryonic palate mesenchymal cell proliferation. Mol Med Rep 16:2538-2546 (2017). PubMed: 28713967
  • Xiang S  et al. Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/ß-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer. Int J Oncol 51:801-811 (2017). PubMed: 28677721
  • Wang X  et al. Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells. Mol Med Rep 16:3894-3900 (2017). PubMed: 28731159
  • Wang L  et al. Mesenchymal stromal cells ameliorate oxidative stress-induced islet endothelium apoptosis and functional impairment via Wnt4-ß-catenin signaling. Stem Cell Res Ther 8:188 (2017). PubMed: 28807051
  • Li S  et al. The Overexpression of CARM1 Promotes Human Osteosarcoma Cell Proliferation through the pGSK3ß/ß-Catenin/cyclinD1 Signaling Pathway. Int J Biol Sci 13:976-984 (2017). PubMed: 28924379
  • Yu P  et al. Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase. Int J Mol Med 40:1426-1434 (2017). PubMed: 28901378
  • Feng F  et al. Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells. Oncol Lett 14:2947-2953 (2017). PubMed: 28928832
  • Tuo H  et al. MiR-324-3p promotes tumor growth through targeting DACT1 and activation of Wnt/ß-catenin pathway in hepatocellular carcinoma. Oncotarget 8:65687-65698 (2017). PubMed: 29029464
  • Liu Z & Zhang H LncRNA plasmacytoma variant translocation 1 is an oncogene in bladder urothelial carcinoma. Oncotarget 8:64273-64282 (2017). PubMed: 28969069
  • Xiong W  et al. Research on the effect of ginseng polysaccharide on apoptosis and cell cycle of human leukemia cell line K562 and its molecular mechanisms. Exp Ther Med 13:924-934 (2017). PubMed: 28450921
  • Dong S  et al. Involvement of RBP4 in all-trans retinoic acid induced cleft palate. Mol Med Rep 16:5915-5923 (2017). PubMed: 28849085
  • Li ZY  et al. Tanshinone IIA induces apoptosis via inhibition of Wnt/ß-catenin/MGMT signaling in AtT-20 cells. Mol Med Rep 16:5908-5914 (2017). PubMed: 28849207
  • Colleoni B  et al. JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21. Oncogene 36:4349-4361 (2017). IP . PubMed: 28368408
  • Zhou JJ  et al. Knockdown of Hotair suppresses proliferation and cell cycle progression in hepatocellular carcinoma cell by downregulating CCND1 expression. Mol Med Rep 16:4980-4986 (2017). PubMed: 28791413
  • Xu Z  et al. LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma. Oncol Rep 38:3659-3667 (2017). PubMed: 29039571
  • Huang B  et al. Suppression of LETM1 by siRNA inhibits cell proliferation and invasion of bladder cancer cells. Oncol Rep 38:2935-2940 (2017). PubMed: 29048663
  • Lu L  et al. Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model. Evid Based Complement Alternat Med 2016:4097398 (2016). PubMed: 27274751
  • Misiewicz-Krzeminska I  et al. Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma. Clin Cancer Res 22:207-17 (2016). PubMed: 26341922
  • Asher M  et al. Ataxin-1 regulates proliferation of hippocampal neural precursors. Neuroscience N/A:N/A (2016). PubMed: 26876606
  • Jin Y & Dai Z USO1 promotes tumor progression via activating Erk pathway in multiple myeloma cells. Biomed Pharmacother 78:264-71 (2016). WB ; Human . PubMed: 26898451
  • Xing Y  et al. Silencing of ILK attenuates the abnormal proliferation and migration of human Tenon's capsule fibroblasts induced by TGF-ß2. Int J Mol Med N/A:N/A (2016). WB ; Human . PubMed: 27315599
  • Zhang QS  et al. Downregulation of SENP1 inhibits cell proliferation, migration and promotes apoptosis in human glioma cells. Oncol Lett 12:217-221 (2016). WB ; Human . PubMed: 27347128
  • Li J  et al. ATF3 suppresses ESCC via downregulation of ID1. Oncol Lett 12:1642-1648 (2016). IHC-P ; Human . PubMed: 27602100
  • Gao K  et al. Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. Int J Mol Med N/A:N/A (2016). WB . PubMed: 27840941
  • Lujic N  et al. Recurrence of giant cell tumour of bone: role of p53, cyclin D1, ß-catenin and Ki67. Int Orthop 40:2393-2399 (2016). PubMed: 27658412
  • Park E  et al. Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats. Evid Based Complement Alternat Med 2016:1428923 (2016). WB ; Rat . PubMed: 27504137
  • Yuan S  et al. Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-?B pathway. Cell Cycle 15:2895-2905 (2016). PubMed: 27436181
  • Xia X  et al. Inhibitor of DNA binding 1 regulates cell cycle progression of endothelial progenitor cells through induction of Wnt2 expression. Mol Med Rep N/A:N/A (2016). WB ; Mouse . PubMed: 27432753
  • Mao M & Wang W SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma. Mol Med Rep 14:881-7 (2016). PubMed: 27221371
  • Wu J  et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis 7:e2339 (2016). WB . PubMed: 27537522
  • Ye GF  et al. Secreted Protein Acidic and Rich in Cysteine Modulates Molecular Arterial Homeostasis of Human Arterial Smooth Muscle Cells In Vitro. J Mol Neurosci 60:509-516 (2016). WB ; Human . PubMed: 27561928
  • Zhao X  et al. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Mol Med Rep 14:1067-74 (2016). WB ; Human . PubMed: 27279418
  • Xia W  et al. Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation. Sci Rep 6:35576 (2016). WB ; Human . PubMed: 27752108
  • Xu J  et al. miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6. Sci Rep 6:28968 (2016). PubMed: 27364926
  • Majaz S  et al. Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression. Cell Biosci 6:47 (2016). PubMed: 27486509
  • He B  et al. Upregulated microRNA-143 inhibits cell proliferation in human nasopharyngeal carcinoma. Oncol Lett 12:5023-5028 (2016). WB ; Human . PubMed: 28105209
  • Han A  et al. p63a modulates c-Myc activity via direct interaction and regulation of MM1 protein stability. Oncotarget 7:44277-44287 (2016). WB ; Human . PubMed: 27341130
  • Feng J  et al. Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells. Eur J Histochem 60:2711 (2016). PubMed: 28076932
  • Yang CX  et al. MicroRNA-320 regulates the radiosensitivity of cervical cancer cells C33AR by targeting ß-catenin. Oncol Lett 12:4983-4990 (2016). WB . PubMed: 28105205
  • Hong Y  et al. miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancer. Sci Rep 6:37421 (2016). WB ; Human . PubMed: 27857177
  • Zhang X  et al. MicroRNA-195 suppresses colorectal cancer cells proliferation via targeting FGF2 and regulating Wnt/ß-catenin pathway. Am J Cancer Res 6:2631-2640 (2016). WB ; Human . PubMed: 27904776
  • Liang L  et al. Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway. Oncotarget 7:82554-82566 (2016). WB ; Rat . PubMed: 27776340
  • Li YI  et al. Increased autophagic response in a population of metastatic breast cancer cells. Oncol Lett 12:523-529 (2016). ICC/IF ; Human . PubMed: 27347175
  • Qu F  et al. MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/ß-catenin pathway. Oncol Lett 11:1592-1596 (2016). WB ; Human . PubMed: 26893786
  • Huang H  et al. Ablation of the Sox11 Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence. J Biol Chem 291:7107-18 (2016). PubMed: 26826126
  • Wu K  et al. miR-483-5p promotes growth, invasion and self-renewal of gastric cancer stem cells by Wnt/ß-catenin signaling. Mol Med Rep 14:3421-8 (2016). PubMed: 27511210
  • Zhu J  et al. Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells. Am J Transl Res 8:5569-5579 (2016). PubMed: 28078027
  • Zhao L  et al. Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering ß-catenin signalling and GADD45G expression. J Cell Mol Med 20:842-54 (2016). WB ; Human . PubMed: 26843424
  • Lee JW  et al. A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress. PLoS One 10:e0122628 (2015). PubMed: 25897662
  • Tan BL  et al. Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/ß-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis. BMC Complement Altern Med 15:205 (2015). WB ; Rat . PubMed: 26122204
  • Markiewicz E  et al. Nonlinear ionizing radiation-induced changes in eye lens cell proliferation, cyclin D1 expression and lens shape. Open Biol 5:150011 (2015). PubMed: 25924630
  • Pozo K  et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget 6:12080-93 (2015). WB . PubMed: 25900242
  • Ralhan R  et al. Immunohistochemical Subcellular Localization of Protein Biomarkers Distinguishes Benign from Malignant Thyroid Nodules: Potential for Fine-Needle Aspiration Biopsy Clinical Application. Thyroid 25:1224-34 (2015). IHC . PubMed: 26131603
  • Wang X  et al. Synergistic control of sex hormones by 17ß-HSD type 7: a novel target for estrogen-dependent breast cancer. J Mol Cell Biol 7:568-79 (2015). PubMed: 25966904
  • Zhang P  et al. Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-a protein turnover. Cell Death Dis 6:e1687 (2015). PubMed: 25766326
  • Ye GD  et al. OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and is Downregulated in Human Colorectal Tumors. Gastroenterology N/A:N/A (2015). PubMed: 26619963
  • Bai M  et al. OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma. Oncol Rep 33:1745-52 (2015). PubMed: 25634023
  • Xu Z  et al. Quantitative Proteomics Reveals That the Inhibition of Na(+)/K(+)-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells. J Proteome Res 14:4594-602 (2015). PubMed: 26491887
  • Gao K  et al. Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells. Am J Cancer Res 5:3210-20 (2015). Human . PubMed: 26693071
  • Gao K  et al. HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma. Biochem Biophys Res Commun 458:849-55 (2015). WB ; Human . PubMed: 25689719
  • Shi J  et al. Regulation of ß-catenin transcription activity by leupaxin in hepatocellular carcinoma. Tumour Biol N/A:N/A (2015). PubMed: 26361959
  • Lan Z  et al. Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro. Int J Mol Med 36:904-10 (2015). PubMed: 26201988
  • Cai JQ  et al. Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics. Tumour Biol N/A:N/A (2015). PubMed: 26307396
  • Ren W  et al. FHL1 inhibits the growth of tongue squamous cell carcinoma cells via G1/S cell cycle arrest. Mol Med Rep 12:3958-64 (2015). PubMed: 26017856
  • Liu Y  et al. Gpr177-mediated Wnt Signaling Is Required for Secondary Palate Development. J Dent Res 94:961-7 (2015). PubMed: 25922332
  • Mirzaa GM  et al. De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome. Nat Genet 46:510-5 (2014). WB ; Human . PubMed: 24705253
  • Wei C  et al. Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer. Proc Natl Acad Sci U S A 111:E601-10 (2014). PubMed: 24449872
  • Brodowska K  et al. Effects of metformin on retinoblastoma growth in vitro and in vivo. Int J Oncol 45:2311-24 (2014). PubMed: 25215935
  • Ito K  et al. Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53-dependent apoptosis without enhancing proliferation. Oncogene N/A:N/A (2013). Mouse . PubMed: 23624920
  • Zhong LP  et al. Elevated cyclin D1 expression is predictive for a benefit from TPF induction chemotherapy in oral squamous cell carcinoma patients with advanced nodal disease. Mol Cancer Ther 12:1112-21 (2013). IHC ; Human . PubMed: 23515614
  • Guo SL  et al. Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. Nat Commun 4:2544 (2013). WB, IHC-P ; Human . PubMed: 24149576
  • Hua Y  et al. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res 19:6242-51 (2013). Mouse . PubMed: 24077352
  • Sreevalsan S & Safe S The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells. Mol Cancer Ther 12:2483-93 (2013). PubMed: 24030632
  • Fu WY  et al. Suppression of liver regeneration affects hepatic graft survival in small-for-size liver transplantation in rats. Hepatol Res : (2012). PubMed: 22882432
  • Feng Z  et al. CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma. PLoS One 6:e26399 (2011). IHC-P ; Human . PubMed: 22065993

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