Overview

  • Product name
    Anti-Cyclin G antibody - C-terminal
    See all Cyclin G primary antibodies
  • Description
    Rabbit polyclonal to Cyclin G - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human Cyclin G aa 249-280 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P51959

  • Positive control
    • HeLa cells; Mouse kidney tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab170389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

WB 1/50 - 1/100. Predicted molecular weight: 34 kDa.

Target

  • Function
    May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
  • Tissue specificity
    High levels in skeletal muscle, ovary, kidney and colon.
  • Sequence similarities
    Belongs to the cyclin family. Cyclin G subfamily.
  • Developmental stage
    Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.
  • Cellular localization
    Nucleus. DNA replication foci after DNA damage.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCNG 1 antibody
    • CCNG antibody
    • CCNG1 antibody
    • CCNG1_HUMAN antibody
    • CYCG1 antibody
    • Cyclin G antibody
    • Cyclin G1 antibody
    • Cyclin-G antibody
    • Cyclin-G1 antibody
    see all

Images

  • Flow cytometric analysis of HeLa cells labeling Cyclin G with ab170389 at 1/10 (right histogram) compared to a negative control cell (left histogram). FITC conjugated Goat anti-rabbit secondary antibodies were used for the analysis.

  • Anti-Cyclin G antibody - C-terminal (ab170389) at 1/50 dilution + Mouse kidney tissue lysates at 35 µg

    Predicted band size: 34 kDa

References

ab170389 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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