- References (3)
Product nameCyclopiazonic acid from Penicillium grisefulvum, Ca2+-ATPase inhibitor
- α-Cyclopiazonic acid
Biological descriptionCell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 5 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Ion pumps / transporter
This product has been referenced in:
- Laursen M et al. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J Biol Chem 284:13513-8 (2009). Read more (PubMed: 19289472) »
- Soler F et al. Cyclopiazonic acid effect on Ca2+-dependent conformational states of the sarcoplasmic reticulum ATPase. Implication for the enzyme turnover. Biochemistry 37:4266-74 (1998). Read more (PubMed: 9521749) »
- Plenge-Tellechea F et al. On the inhibition mechanism of sarcoplasmic or endoplasmic reticulum Ca2+-ATPases by cyclopiazonic acid. J Biol Chem 272:2794-800 (1997). Read more (PubMed: 9006919) »