Key features and details
- Somatostatin antagonist.
- CAS Number: 84211-54-1
- Purity: > 97%
- Soluble in DMSO to 1mg/ml
- Form / State: Solid
- Source: Synthetic
Product nameCyclosomatostatin, Somatostatin antagonist.
Somatostatin antagonist with various biological activities. Blocks the effect of somatostatin on β-adrenergic function and CRF-induced suppression of gastric empyting, ACh release and growth hormone, insulin, and glucagon release. May act as potent antiproliferative agonist in some cell lines.
SequenceFWKT (Modifications: N-terminal aminoheptanoyl; Trp-2 = D-Trp; Thr-4 = Thr(Bn); Cyclised: 1-4)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 1mg/ml
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141211 has been referenced in 1 publication.
- Li N et al. Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents. Cell Death Dis 9:682 (2018). PubMed: 29880854