Key features and details
- TPA/PMA inhibitor
- CAS Number: 83602-39-5
- Purity: > 96%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Fusarium solani
Product nameCyclosporin H, TPA/PMA inhibitor
Biological descriptionTPA/PMA inhibitor. Selective inhibitor of formyl peptide receptors (Ki = 0.1 µM). Inhibits Ca2+/calmodulin dependent EF-2 phosphorylation. Inhibits FMLP-induced superoxide anion formation (IC50 = 40 nM). Multiple biological effects.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO and in ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141923 has been referenced in 1 publication.
- Contino S et al. Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology. Front Physiol 8:796 (2017). PubMed: 29085303