Anti-CYLN2 antibody - C-terminal (ab173542)

Overview

  • Product name
    Anti-CYLN2 antibody - C-terminal
    See all CYLN2 primary antibodies
  • Description
    Rabbit polyclonal to CYLN2 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human CYLN2 aa 910-940 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. NP_003379.3
    Database link: Q9UDT6

  • Positive control
    • Mouse brain tissue lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab173542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 116 kDa.

Target

  • Function
    Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operates in the control of brain-specific organelle translocations.
  • Involvement in disease
    Note=CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • Sequence similarities
    Contains 2 CAP-Gly domains.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton. Associated with the cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAP GLY domain containing linker protein 2 antibody
    • CAP-Gly domain-containing linker protein 2 antibody
    • CLIP 115 antibody
    • CLIP antibody
    • CLIP-115 antibody
    • Clip2 antibody
    • CLIP2_HUMAN antibody
    • cytoplasmic linker 2 antibody
    • Cytoplasmic linker protein 115 antibody
    • Cytoplasmic linker protein 2 antibody
    • KIAA0291 antibody
    • MGC11333 antibody
    • restin antibody
    • Similar to RESTIN (CYTOPLASMIC LINKER PROTEIN 170 ALPHA 2) antibody
    • WBSCR3 antibody
    • WBSCR4 antibody
    • Williams Beuren syndrome chromosome region 3 antibody
    • Williams Beuren syndrome chromosome region 4 antibody
    • Williams-Beuren syndrome chromosomal region 3 protein antibody
    • Williams-Beuren syndrome chromosomal region 4 protein antibody
    • WSCR3 antibody
    • WSCR4 antibody
    see all

Images

  • Anti-CYLN2 antibody - C-terminal (ab173542) at 1/100 dilution + Mouse brain tissue lysates at 35 µg

    Predicted band size: 116 kDa

References

ab173542 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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