Key features and details
- Rabbit polyclonal to CYP26A1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-CYP26A1 antibody
See all CYP26A1 primary antibodies
DescriptionRabbit polyclonal to CYP26A1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Cow, Monkey
Recombinant fragment, corresponding to a region within amino acids 246-497 of Human CYP26A1 (O43174).
- 293T whole cell lysate; Human hepatoma and Mouse muscle tissues.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
Our Abpromise guarantee covers the use of ab151968 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 56 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionPlays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Tissue specificityHighest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
Sequence similaritiesBelongs to the cytochrome P450 family.
Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
- Information by UniProt
- CP26 antibody
- CP26A_HUMAN antibody
- CYP26 antibody
Anti-CYP26A1 antibody (ab151968) at 1/1000 dilution + 293T whole cell lysate at 30 µg
Predicted band size: 56 kDa
7.5% SDS PAGE
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling CYP26A1 with ab151968 at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded Mouse muscle tissue labeling CYP26A1 with ab151968 at 1/500 dilution.
ab151968 has been referenced in 1 publication.
- Gu AQ et al. Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy. J Cell Mol Med 23:5403-5414 (2019). PubMed: 31148354