Overview

  • Product name

  • Description

    Rabbit polyclonal to CYP26A1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow, Monkey
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 246-497 of Human CYP26A1 (O43174).

  • Positive control

    • 293T whole cell lysate; Human hepatoma and Mouse muscle tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab151968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
  • Tissue specificity

    Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CP26 antibody
    • CP26A_HUMAN antibody
    • CYP26 antibody
    • CYP26A 1 antibody
    • cyp26a1 antibody
    • Cytochrome P450 26A1 antibody
    • Cytochrome P450 family 26 subfamily A polypeptide 1 antibody
    • Cytochrome P450 retinoic acid-inactivating 1 antibody
    • cytochrome P450, family 26, subfamily A, polypeptide 1 antibody
    • cytochrome P450, subfamily XXVIA, polypeptide 1 antibody
    • Cytochrome P450RAI antibody
    • hP450RAI antibody
    • OTTHUMP00000020102 antibody
    • OTTHUMP00000020103 antibody
    • P450 antibody
    • P450 retinoic acid inactivating 1 antibody
    • P450RAI antibody
    • P450RAI1 antibody
    • Retinoic acid 4 hydroxylase antibody
    • Retinoic acid 4-hydroxylase antibody
    • Retinoic acid metabolizing cytochrome antibody
    • Retinoic acid-metabolizing cytochrome antibody
    see all

Images

  • Anti-CYP26A1 antibody (ab151968) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size: 56 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling CYP26A1 with ab151968 at 1/500 dilution.
  • Immunohistochemical analysis of paraffin-embedded Mouse muscle tissue labeling CYP26A1 with ab151968 at 1/500 dilution.

References

ab151968 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151968.
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