Overview

  • Product name

    Anti-CYP27A1 antibody - C-terminal
    See all CYP27A1 primary antibodies
  • Description

    Rabbit Polyclonal to CYP27A1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Fusion protein corresponding to Human CYP27A1 (C terminal). Fusion protein corresponding to residues near the C terminal of human CYP27A1. The identity of the protein fusion partner is GST.
    Database link: Q02318

  • Positive control

    • Mouse liver and Human fetal liver tissue lysates; Human liver cancer tissue.

Applications

Our Abpromise guarantee covers the use of ab197933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 60 kDa.
IHC-P 1/25 - 1/100.

Target

  • Function

    Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
  • Pathway

    Hormone biosynthesis; cholecalciferol biosynthesis.
  • Involvement in disease

    Cerebrotendinous xanthomatosis
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Mitochondrion membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 12-alpha-triol 27-hydroxylase antibody
    • 5-beta-cholestane-3-alpha antibody
    • 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase antibody
    • 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase antibody
    • 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase antibody
    • 7-alpha antibody
    • Cholestanetriol 26 monooxygenase antibody
    • CP27 antibody
    • CP27A_HUMAN antibody
    • CTX antibody
    • CYP antibody
    • CYP27 antibody
    • CYP27A1 antibody
    • Cytochrome P 450C27/25 antibody
    • Cytochrome P-450C27/25 antibody
    • Cytochrome P450 27 antibody
    • Cytochrome P450 27 mitochondrial antibody
    • Cytochrome P450 family 27 subfamily A member 1 antibody
    • Cytochrome P450 family 27 subfamily A polypeptide 1 antibody
    • Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1 antibody
    • mitochondrial antibody
    • Sterol 26 hydroxylase antibody
    • Sterol 26 hydroxylase mitochondrial antibody
    • Sterol 26-hydroxylase antibody
    • Sterol 27 hydroxylase antibody
    • Sterol 27-hydroxylase antibody
    • Vitamin D(3) 25 hydroxylase antibody
    • Vitamin D(3) 25-hydroxylase antibody
    see all

Images

  • All lanes : Anti-CYP27A1 antibody - C-terminal (ab197933) at 1/200 dilution

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : Human fetal liver tissue lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 60 kDa


    Exposure time: 7 minutes
  • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling CYP27A1 with ab197933 at 1/25.

References

ab197933 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197933.
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