Overview

  • Product name

  • Description

    Rabbit polyclonal to CYP2A13
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human CYP2A13 aa 399-424.
    Sequence:

    LRDPRFFSNPRDFNPQHFLDKKGQFK


    Database link: Q16696

  • Positive control

    • IHC-P: Human liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab223785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.
  • Tissue specificity

    Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CP2AD_HUMAN antibody
    • CPAD antibody
    • CYP2A antibody
    • CYP2A13 antibody
    • CYPIIA13 antibody
    • Cytochrome P450 2A13 antibody
    • Cytochrome P450 family 2 subfamily A member 13 antibody
    • CYTOCHROME P450, SUBFAMILY IIA, POLYPEPTIDE 13 antibody
    see all

Images

  • Paraffin-embedded human liver tissue stained for CYP2A13 using ab223785 at 1/50 dilution in immunohistochemical analysis.

References

ab223785 has not yet been referenced specifically in any publications.

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