Overview

  • Product name
    Anti-CYP2C18 antibody - C-terminal
    See all CYP2C18 primary antibodies
  • Description
    Rabbit polyclonal to CYP2C18 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CYP2C18 aa 456-485 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P33260

  • Positive control
    • Human hepatocarcinoma tissue; HL-60 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab175982 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 56 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Cellular localization
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • Database links
  • Alternative names
    • (S) mephenytoin hydroxylase associated cytochrome P450 antibody
    • CPCI antibody
    • CYP2C 18 antibody
    • CYP2C antibody
    • CYP2C17 antibody
    • CYPIIC18 antibody
    • Cytochrome P450 2C18 antibody
    • Cytochrome P450 6B/29C antibody
    • Cytochrome P450 family 2 subfamily C polypeptide 18 antibody
    • Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 17 antibody
    • Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 18 antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • P450 6B/29C antibody
    • P450IIC17 antibody
    • Unspecific monooxygenase antibody
    see all

Images

  • Anti-CYP2C18 antibody - C-terminal (ab175982) at 1/1000 dilution + HL-60 cell line lysates at 35 µg

    Predicted band size: 56 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human hepatocarcinoma tissue labeling CYP2C18 with ab175982 at 1/50 dilution. Detection utilised peroxidase conjugation of the secondary antibody and DAB staining.

References

ab175982 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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