Anti-CYP2C8 antibody (ab88904)
Key features and details
- Mouse polyclonal to CYP2C8
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CYP2C8 antibody
See all CYP2C8 primary antibodies -
Description
Mouse polyclonal to CYP2C8 -
Host species
Mouse -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Full length Human CYP2C8 (AAH20596.1, amino acids 1-490)
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Positive control
- Human liver tissue lysate; CYP2C8 transfected 293T cell lysate.
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General notes
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab88904 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| WB |
Human
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 56 kDa.
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| Notes |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 56 kDa. |
Target
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Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol). -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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Database links
- Entrez Gene: 1558 Human
- Omim: 601129 Human
- SwissProt: P10632 Human
- Unigene: 709188 Human
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Alternative names
- CP2C8_HUMAN antibody
- CPC8 antibody
- CYP2C8 antibody
see all
Images
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Western blot - Anti-CYP2C8 antibody (ab88904)Anti-CYP2C8 antibody (ab88904) at 1/500 dilution + human liver tissue lysate at 50 µg
Predicted band size: 56 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted? -
Western blot - Anti-CYP2C8 antibody (ab88904)All lanes : Anti-CYP2C8 antibody (ab88904) at 1/500 dilution
Lane 1 : CYP2C8 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 56 kDa
Observed band size: 48 kDa why is the actual band size different from the predicted?
Datasheets and documents
References (0)
ab88904 has not yet been referenced specifically in any publications.
