Overview

  • Product name

  • Description

    Rabbit polyclonal to CYP2C9
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein corresponding to Human CYP2C9 aa 1-162. (Full length, BC020754).
    Sequence:

    MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI SKSLTNLSKV YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF PLAERANRGF GIVFSNGKKW KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTK GG


    Database link: P11712-2

  • Positive control

    • Human liver cancer tissue.
  • General notes

     This product was previously labelled as Cytochrome P450 2C9

     

Properties

Applications

Our Abpromise guarantee covers the use of ab197928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/35 - 1/200.

Target

  • Function

    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • (R)-limonene 6-monooxygenase antibody
    • (S)-limonene 6-monooxygenase antibody
    • (S)-limonene 7-monooxygenase antibody
    • CP2C9_HUMAN antibody
    • CPC9 antibody
    • CYP2C antibody
    • CYP2C10 antibody
    • CYP2C9 antibody
    • CYPIIC9 antibody
    • cytochrome P-450 S-mephenytoin 4-hydroxylase antibody
    • Cytochrome P-450MP antibody
    • Cytochrome P450 2C9 antibody
    • Cytochrome P450 MP-4 antibody
    • Cytochrome P450 MP-8 antibody
    • Cytochrome P450 PB-1 antibody
    • Cytochrome P450, family 2, subfamily C, polypeptide 9 antibody
    • Cytochrome p4502C9 antibody
    • flavoprotein-linked monooxygenase antibody
    • MGC149605 antibody
    • MGC88320 antibody
    • microsomal monooxygenase antibody
    • OTTHUMP00000020135 antibody
    • P450 MP antibody
    • P450 PB 1 antibody
    • P450 PB1 antibody
    • P450IIC9 antibody
    • P450MP antibody
    • S mephenytoin 4 hydroxylase antibody
    • S-mephenytoin 4-hydroxylase antibody
    • xenobiotic monooxygenase antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling CYP2C9 with ab197928 at 1/35 dilution.

References

ab197928 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197928.
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