Anti-CYP2D6 antibody (ab137426)
Key features and details
- Rabbit polyclonal to CYP2D6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-CYP2D6 antibody
See all CYP2D6 primary antibodies -
Description
Rabbit polyclonal to CYP2D6 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Monkey -
Immunogen
Recombinant fragment corresponding to Human CYP2D6 aa 268-457.
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Positive control
- A431, HeLa, HepG2, MOLT4 and Raji cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137426 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 56 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 56 kDa. |
Target
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Function
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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Database links
- Entrez Gene: 1565 Human
- Omim: 124030 Human
- SwissProt: P10635 Human
- Unigene: 648256 Human
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Alternative names
- Cholesterol 25-hydroxylase antibody
- CP2D6_HUMAN antibody
- CPD6 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab137426 has been referenced in 2 publications.
- Tanino T et al. Hepatic Cytochrome P450 Activity and Nitric Oxide Production During Multiple Ovalbumin Challenges. Eur J Drug Metab Pharmacokinet N/A:N/A (2018). PubMed: 30411300
- Tanino T et al. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice. Drug Metab Dispos 44:1950-1957 (2016). PubMed: 27694226